Booster Effect of mRNA Vaccine After Complete Vaccination With Sinos: an Observational Study
试验速览
- 阶段
- 不适用
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- IgG RBD levels
研究概览
简要总结
In most parts of the world, mRNA vaccines were used to provide protection to population against COVID 19. However, in some countries, including Pakistan, traditional viral vaccines named as Sinovac and Sinopharm were used for mass level immunization. Though these vaccines were approved by WHO, their efficacy had been questioned.
Now after recommendation of booster doses, we aim to see the effect of mRNA vaccine as a booster dose after Sinovac and Sinopharm in terms of antibody response. (IgG RBD SARS CoV2)
详细描述
In most parts of the world, mRNA vaccines were used to provide protection to population against COVID 19. However, in some countries, including Pakistan, traditional viral vaccines named as Sinovac and Sinopharm were used for mass level immunization. Though these vaccines were approved by WHO, their efficacy had been questioned.
Now after recommendation of booster doses, we aim to see the effect of mRNA vaccine (BNT162b2, pfizer) as a booster dose after Sinovac and Sinopharm in terms of antibody response. (IgG RBD SARS CoV2).
The antobody IgG RBD levels will be checked before the booster dose and then after 3 weeks of the booster.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •people who have received two doses of sinopharm or sinovac and six months have passed after the second dose
排除标准
- •people getting one shot of sinopharm or sinovac or got vaccine other than sinopharm and sinovac.
结局指标
主要结局
IgG RBD levels
时间窗: after 3 weeks of booster vaccine dose
to see the effect of booster vaccine after 3 weeks in terms of IgG RBD
次要结局
未报告次要终点