Comparison of Difference Histamine Concentration (1, 5 and 10 mg/ml) for Skin Prick Test Positive Control
Not Applicable
Completed
- Conditions
- Immediate Hypersensitivity
- Interventions
- Procedure: SPT
- Registration Number
- NCT02561429
- Lead Sponsor
- Mahidol University
- Brief Summary
Skin prick test (SPT) was used for diagnostic test for type 1 hypersensitivity. The efficacy and safety of SPT were proved. The positive control of SPT is histamine.
In Thailand, the most common concentration of histamine for SPT is 10 mg/ml. However, in some practice they use other concentration (1, 2.5 mg/ml).
This study will find the proper concentration of histamine for positive control use in SPT.
- Detailed Description
Appropriate concentration of histamine positive control is important in interpretation the result of skin prick test.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 180
Inclusion Criteria
- Parcitipate person who attented allergy clinic, ENT clinic
- Legible in Thai language
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Exclusion Criteria
- Patient cannot withhold antihistamine drug
- Pragnancy and lactation mother
- comorbid disease such as cardiac disease, liver, renal, hypertension and severe asthma
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description SPT of histamine SPT SPT of histamine concentration 1, 5 and 10 mg/ml
- Primary Outcome Measures
Name Time Method Mean wheal diameters of SPT of different histamine concentrations. 1 years compare mean wheal diameters of histamine concentration 1,5, and 10 mg/ml
- Secondary Outcome Measures
Name Time Method Mean wheal diameters of SPT of local and imported histamine positive concentration 1 year compare mean wheal diameters of imported histamine 1 mg/ml to local histamine
Trial Locations
- Locations (1)
Faculty of Medicine Siriraj Hospital
🇹ðŸ‡Bangkoknoi, Bangkok, Thailand