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DRIGITAT: Doppler Ratio In fetal Growth restriction Intervention Trial At (near) Term

Conditions
Fetal growth restrion, foetale groeirestrictie
Registration Number
NL-OMON29445
Lead Sponsor
Academisch Medische Centrum (AMC) - Amsterdam
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
185
Inclusion Criteria

o Inclusion criteria cohort:
- Singleton pregnancy
- Identified SGA (estimated fetal weight or fetal abdominal circumference below 10th percentile)
- 32+0 – 37+0 weeks of gestation

o Inclusion in RCT (in addition to the above-mentioned criteria)
- Abnormal UmbilicoCerebral Ratio (UCR): ≥0.8 on at least 2 occasions with an interval of at least one day
AND
- EFW and/or FAC OR
- EFW and/or FAC <p10 AND 36+0 – 37+0 weeks of gestation

Exclusion Criteria

- Maternal age <18 years

- Multiple pregancies

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
7-point average difference MDI/PDI Bayley-III at 2 years
Secondary Outcome Measures
NameTimeMethod
Composite outcome of neonatal morbidity appropriate for late preterm gestations, perinatal mortality, mode of delivery, maternal quality of life, costs.
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