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Education Impact on Rehabilitation of Hospitalized Patients With Pneumonia and COVID-19

Not Applicable
Completed
Conditions
Pneumonia Due to COVID-19
Interventions
Other: Education program
Other: Pulmonary rehabilitation
Registration Number
NCT06522724
Lead Sponsor
University of Rzeszow
Brief Summary

The planned research will enable the assessment of rehabilitation's effects using two pulmonary rehabilitation models: conventional and supplemented with an education program for patients hospitalized due to pneumonia with confirmed COVID-19.

Detailed Description

The planned group size is 60 patients diagnosed with pneumonia and confirmed COVID-19. The given population was calculated based on the sampling calculator, considering the following parameters: fraction size, confidence level, and maximum error. Eligible patients will be randomly divided into two groups: a study group (30 patients) undergoing pulmonary rehabilitation supplemented with an education program, and a control group (30 patients) undergoing conventional pulmonary rehabilitation. Patients of both groups will be included in a 14-day rehabilitation program (Monday to Saturday). Treatments and therapies will be continued for a maximum of three hours daily. The program will be applied individually to each patient and include in-bed assisted exercises, airway clearance techniques, effective cough exercises, pursed-lips breathing, exercises to strengthen the diaphragm and intercostal muscles and cardiopulmonary exercises. Patients from the study group will additionally undergo daily education using an original brochure containing information about self management during the treatment process, the benefits of appropriately adapted physical activity, practical tips on airway clearance techniques or physical exercise. The test will be performed two times: before the start of rehabilitation and after completing the rehabilitation program. The patients' condition and the rehabilitation effects will be assessed using the following measures:

* Vital capacity (Voldyne 5000)

* Oxygen saturation (pulse oximeter)

* Acid-base balance (gasometry)

* Fatigue (modified Borg scale)

* Physical performance (Sit-to-Stand Test)

* Dyspnea assessment (MRC dyspnea scale)

* Anxiety and depression (HADS scale)

* Activities of daily living (Barthel scale)

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
100
Inclusion Criteria
  • Hospitalization due to pneumonia due to COVID-19
  • Positive SARS-COV-2 PCR test
  • Independence in in-bed sitting position with lower extremities placed on the floor
  • Age 40 y.o. to 70 y.o.
  • No additional respiratory support (e.a. cardiopulmonary bypass machine, ventilator)
  • Informed, voluntary consent to participate in research.
Exclusion Criteria
  • Hospitalization due to pneumonia with negative SARS-COV-2 PCR test
  • Unstable medical condition hindering performing the examination
  • Age under 40 y.o. and over 70 y.o.
  • Cognitive deficits impairing the ability to understand and execute commands
  • Concomitant oncological, neurological, orthopedic, and psychiatric diseases may affect the examined persons' circulatory and respiratory functions, functional efficiency, quality of life, and emotional state.
  • Failure to complete a 14-day rehabilitation program
  • Lack of informed, voluntary consent to participate in research

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Education program and Pulmonary rehabilitationEducation programConventional pulmonary rehabilitation coupled with original education program.
Pulmonary rehabilitationPulmonary rehabilitationConventional pulmonary rehabilitation
Education program and Pulmonary rehabilitationPulmonary rehabilitationConventional pulmonary rehabilitation coupled with original education program.
Primary Outcome Measures
NameTimeMethod
Vital capacity (Voldyne 5000)Second examination- at the end of the 14-day rehabilitation program

Measurements will be performed with certified motivational spirometer, Voldyne 5000. Patient, in a sitting position, will inhale as much air as possible starting from residual volume (RV) level and approach to vital capacity (VC) level. The result will be read from the scale placed on the wall of the device.

Oxygen saturationSecond examination- at the end of the 14-day rehabilitation program

Measurements will be performed with pulse oximeter and the parameter analyzed will be SpO2 (oxygen saturation by pulse oximetry; percentage of oxygen in patients' blood).

Acid-base balanceSecond examination- at the end of the 14-day rehabilitation program

The gasometry results will be taken from patients' medical documentation. The parameters analyzed will be oxygen pressure (pO2) and carbon dioxide pressure (pCO2).

Secondary Outcome Measures
NameTimeMethod
Activities of daily living assesment using Barthel scaleSecond examination- at the end of the 14-day rehabilitation program

The Barthel Scale will be used to measure patient's ability to perform activities of daily living (ADLs) independently, with scores ranging from 0 (completely dependent) to 100 (completely independent).

Fatigue assessment using modified Borg scaleSecond examination- at the end of the 14-day rehabilitation program

Fatigue will be examined during physical activity and the level of fatigue will be marked on a scale from 1 (no fatigue) to 10 (very very hard fatigue).

Physical performance assessment by Sit-to-Stand Test (STS)Second examination- at the end of the 14-day rehabilitation program

The test will be performed starting in sitting position in the chair with straight back, feet flat on the floor, and arms crossed over the chest or placed on the thighs. The patient will be instructed to stand up fully from the seated position and then sit back down as quickly and safely as possible during 30 seconds (number of standings in 30 seconds).

Dyspnea assessment with Medical Research Council dyspnea scaleSecond examination- at the end of the 14-day rehabilitation program

Perceived breathlessness degree will be marked on a scale 0 (no breathlessness) to 4 (breathlessness at rest).

Anxiety and depression assessment using HADS scaleSecond examination- at the end of the 14-day rehabilitation program

The scale consists of 16 statements to which the respondent refers on a four-point scale. Eight statements are used to measure anxiety and depression, each of which is rated on a scale of 0 to 3 points. The cut-off threshold is 7 points for depression and 7 points for anxiety. The intensity of depressed mood and anxiety will be analyzed.

Trial Locations

Locations (1)

University of Rzeszów

🇵🇱

Rzeszów, Poland

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