Randomized controlled study to compare the efficacy of Dashmool Visva decoction with Punarnava Mandoor in improving Haemoglobin level in Kaphaj Pandu (Iron Deficiency Anaemia)
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Improvement in Haemoglobin Level
研究概览
简要总结
Pandu is a rasa pradoshaj vikar, it is due to excessive exacerbations of three doshasespecially pitta afflicts dhatus as a result complexion, strength, unctuousness and other property also get too much diminished due to morbidity of dosha and dushyaand then blood, fat and ojas get exceedingly reduced leading to development of Pandu roga. Pandu is a symptom as well as a disease characterized by pallor discolouration.
Anaemia is a condition in which the number of red blood cells or the Haemoglobin concentration within them is lower than normal. Haemoglobin is needed to carry oxygen and if you have too few or abnormal red blood cells, or not enough Haemoglobin, there will be a decreased capacity of the blood to carry oxygen to the body’s tissues. This results in symptoms such as Fatigue, Weakness, Dizziness and Shortness of breath, among others. The signs include loss of normal colour in the skin and also in the lips, tongue, nail beds and the blood vessels in the sclera part of the eye. Without treatment, Anaemia can worsen and become underlying causes of chronic ill health, such as impaired foetal development during pregnancy, delayed cognitive development and increased risk of infection in young children and reduced physical capacity in all people.
This study is to compare the efficacy of Dashmool Visva decoction and Punarnava Mandoor in the management of kaphaj Pandu (Iron Deficiency Anaemia). Total no. of patient is 50, 25 in each group. In group A Punarnava Mandoor is given in dose of 2 tablets (250mg each) twice a day after 1 hour of meal with lukewarm water for 45 days. In group B Dashmool Visva kwath is given in dose of 40 ml twice a day after 1 hour of meal with lukewarm water for 45 days.
Study design is single centered, open label, randomized, interventional type, comparative study.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Open Label
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •Patients not suffering from any severe disease other than Iron deficiency Anaemia.
- •Haemoglobin level -between 6-11 gm/dl.
- •Patients who can take medicines orally.
排除标准
- •Patients suffering from any other systemic diseases like Renal disorders, Heart disease, Cancer, acquired immune deficiency syndrome etc.
- •Age <18 years and more than 60 years
- •Haemoglobin level-below 6 gm/dl and more than 11 gm/dl.
- •Pregnant women and lactating mothers.
- •Patients already taking any medicine for Anaemia.
结局指标
主要结局
Improvement in Haemoglobin Level
时间窗: Day0 | Day15 | Day30 | Day45 | Day60
次要结局
- Improvement in Following Clinical Features:(1-Pandutaa (Pallor), 2-Swash (Dyspnoea), 3-Bhrama (Dizziness))
