A study to determine the causes and prevalence of critical illness amongst children presenting to participating hospitals in resource-limited settings
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2021/12/038425
- Lead Sponsor
- Tata Memorial Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Inclusion criteria include:
1. Children (aged 28 days to 14 years)
2. Children evaluated in the ED for an acute illness or injury or admitted to an inpatient unit at a participating study site, who are discharged home after ED evaluation, who died in the ED or are transferred to a higher level of care.
Exclusion Criteria
Exclusion criteria include:
Children presenting for a follow-up visit, vaccinations, suture removal (or other non-acute complaint) or children with a corrected gestational age less than 42 weeks.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Prevalence of acute critical illness, defined as death within 48 hours of presentation to the hospital, including ED mortality; OR admission/transfer to an HDU or ICU; OR transfer to another institution with a higher level of care; OR receiving critical care-level interventions (vasopressor infusion, invasive mechanical ventilation, non-invasive mechanical ventilation) regardless of location in the hospitalTimepoint: 48 hours of presentation
- Secondary Outcome Measures
Name Time Method Etiology of critical illness, in-hospital mortality, early mortality (death within 48 hours of presentation), cause of death, resource utilization, and change in neurocognitive status from premorbid state from admission to discharge (Pediatric Overall Performance Category [POPC] and Pediatric Cerebral Performance Category [PCPC])Timepoint: 48 hours of presentation