Comparison Between Two Endoscopic Treatments of Bleeding Internal Hemorrhoids:Band Ligation and Electrocoagulation Probe
Not Applicable
Completed
- Conditions
- Hemorrhoids
- Registration Number
- NCT00630669
- Lead Sponsor
- University of California, Los Angeles
- Brief Summary
The purpose of this study is to determine which treatment, band ligation (placing rubber bands around the hemorrhoids) or BICAP electrocoagulation (using electricity to cauterize) is safer and more effective endoscopic treatment for bleeding internal hemorrhoids.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 45
Inclusion Criteria
- Grade II or III internal hemorrhoids with chronic rectal bleeding, which failed at least 8 weeks of intensive medical therapy.
- Age over 18 years
- A life expectancy of at least 24 months
- A signed written informed consent
Exclusion Criteria
- The patient was uncooperative or could not return for routine outpatient follow-up
- Severe or end-stage co-morbid illness
- Prior endoscopic or surgical treatment of hemorrhoids within the past 6 months
- Ongoing need for anticoagulation therapy or high doses of aspirin or non-steroidal antiinflammatory agents
- Presence of severe rectal pain
- Recently thrombosed internal or external hemorrhoids
- Anal stricture,fissure, fistula,or abscess
- Rectal carcinoma or bleeding distal colonic polyp
- Rectal varices
- Acute or chronic colitis
- Rectal prolapse
- Radiation telangiectasia of the rectum
- Prothrombin time >3 seconds over control
- Platelet count <75,000
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method treatment success rate one year
- Secondary Outcome Measures
Name Time Method treatment complication rate one year
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What are the molecular mechanisms underlying hemorrhoid bleeding and how do they inform endoscopic treatment strategies?
How does endoscopic band ligation compare to bipolar electrocoagulation in treating internal hemorrhoids?
Are there specific biomarkers that predict response to endoscopic hemorrhoid treatments like band ligation or electrocoagulation?
What are the potential adverse events associated with BICAP electrocoagulation versus band ligation for internal hemorrhoids?
What combination therapies or alternative approaches have been explored for managing bleeding internal hemorrhoids beyond band ligation and electrocoagulation?
Trial Locations
- Locations (1)
Rome Jutabha,MD
🇺🇸Los Angeles, California, United States
Rome Jutabha,MD🇺🇸Los Angeles, California, United States