An Online Intervention to Reduce E-cigarette Use and Susceptibility to Smoking in Young Adults

Not Applicable

Not yet recruiting

• Conditions: E-cigarette Use
• Interventions: Behavioral: Live Free From E-cigarettes

• Registration Number: NCT06129123
• Lead Sponsor: University of Southern California

Brief Summary

The goal of this intervention development and pilot clinical trial is to determine whether receiving the brief online intervention results in greater reductions in past 7-day e-cigarette use frequency and smoking susceptibility over an 8-week period compared to receiving the control condition in young adults who currently use e-cigarettes. Participants in the experimental condition will be asked to complete the 30-minute mobile-based program. Participants in the assessment-only control will be given the option to access the intervention after they complete their final survey at 8 weeks. All participants will complete our online surveys at baseline as well as 2-weeks, 4-weeks, and 8-weeks post-randomization. Researchers will compare outcomes among the intervention and control groups to determine the efficacy of the intervention.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-11-08
• Study First Submitted QC: 2023-11-08
• Study First Posted: 2023-11-13
• Status Verified: 2025-03
• Last Update Submitted: 2025-03-25
• Last Update Posted: 2025-03-30
• Study Start: 2025-06-05
• Primary Completion: 2026-03-01
• Study Completion: 2026-04-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• be between the ages of 18 to 24
• be able to read English
• report vaping at least one day per week in the past month
• report no history of cigarette use at screening and baseline.

Exclusion Criteria

• reporting severe mental health, illicit drug use, or alcohol use disorder
• currently receiving nicotine cessation services

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Intervention	Live Free From E-cigarettes	Participants will be asked to complete a 30-minute intervention that is accessible on a mobile device, delivered via a webpage, and personalized to their individual vaping behavior and beliefs (based on the baseline surveys). The intervention will contain personalized normative feedback (PNF), Motivational Enhancement (ME), and education. Participants will complete assessments at baseline as well as 2-weeks, 4-weeks, and 8-weeks post randomization.

Primary Outcome Measures

Name	Time	Method
E-cigarette Use	8 weeks	Participants will report the number of (1) days they vaped, (2) times they picked up their device to vape per day, and (3) puffs they took before putting their vaping device away per day in the past 7 days and 30 days
Smoking Susceptibility	8 weeks	4-item Expanded Susceptibility to Smoking Index (ESSI)

Secondary Outcome Measures

Name	Time	Method
Perceived harms and benefits of vaping	8 weeks	Using the 21-item Short Form Vaping Consequences Questionnaire (S-VSQ), participants will rate the likelihood that each consequence will occur when they vape.
Perceived harms and benefits of smoking	8 weeks	Using the 21-item Short Form Smoking Consequences Questionnaire (S-SCQ), participants will rate the likelihood that each consequence will occur when they smoke.
Motivation to vape	8 weeks	Participants will select which option best describes their interest in e-cigarette use: plan to stop (coded as 1), decrease (2), continue (3) or increase (4) vaping.
Motivation to smoke	8 weeks	Participants will report if they plan to start smoking (yes/no).
Quitting vaping self-efficacy	8 weeks	Participants rate their confidence about quitting vaping "someday" and "in the next 6 months" on a 5-point scale.
Vaping quit attempts	8 weeks	During follow-up assessments, participants will report on the number of times they have stopped vaping for one day or longer because they were trying to quit vaping.