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临床试验/NCT03782766
NCT03782766已完成不适用

Mandibular Second Molar Protraction Assisted by and Piezocision

Jordan University of Science and Technology0 个研究点目标入组 26 人开始时间: 2015年9月2日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
26
主要终点
Rate of second molar protraction

研究概览

简要总结

This study was conducted to compare the rate of second molar protraction, level of Interleukin1-β in gingival crevicular fluid, periodontal health (gingival index, plaque index, and periodontal pocket depth) and perception of pain in patients treated by molar protraction with piezocision vs control (no piezocision).

详细描述

Twenty-six subjects (39 Molars) who presented with at least one extracted mandibular first molar were selected to participate in the study. The subjects were subdivided into one of 3 groups as follows: group 1 consisted of 18 molars (13 molars from patients with bilateral first molar extraction space and 5 molars from patients with unilateral first molar extraction space) where piezocision was performed immediately before molar protraction; group 2 consisted of 21 molars (13 from patients with bilateral first molar extraction space and 8 molars from patients with unilateral first molar extraction space) where molar protraction was performed with no piezocision; group 3 consisted of 21 molars (group 2 subjects where piezocision was carried on after 3 months of molar protraction with no piezocision. After reaching 0.019X0.025" SS arch wire, NiTi coil spring was used for space closure (protraction force was 150g) attached from the lower second molar hook to the head of the mini-screw. Piezocision was performed by making 2 vertical incisions mesial and distal to the extraction space. Piezotome was inserted in the incisions previously made and bone cuts were done with a length up to mucogingival line and depth of 3 mm.

Gingival crevicular fluid (GCF) sample was obtained from the mesiogingival side of the lower second permanent molar with use of Periopaper. GCF sample was repeated 1 day, 1 week and 4 weeks after molar protraction with piezocision or with no piezocision. Pain was assessed using visual analog scale (VAS). Patients were requested to report the level of pain for 7 consecutive days.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment

入排标准

年龄范围
20 Years 至 27 Years(Adult)
性别
All
接受健康志愿者
是

入选标准

  • •age range from 20 to 27 years
  • •at least one extracted mandibular first molar (first molar extracted more than one year ago and residual extraction space more than 5 mm)
  • •Class 1 malocclusion where molar protraction is indicated
  • •all permanent teeth are present except for the extracted mandibular first molar/molars.

排除标准

  • •Ggingival index score > 2
  • •Plaque index score > 2
  • •Probing depth > 4mm
  • •Previous orthodontic treatment
  • •Systemic disease and

研究组 & 干预措施

piezosurgery

Experimental

group 1 consisted of 18 molars (13 molars from patients with bilateral first molar extraction space and 5 molars from patients with unilateral first molar extraction space) where piezocesion was performed immediately before molar protraction

干预措施: Piezocision (Procedure)

No piezocision

No Intervention

group 2 consisted of 21 molars (13 from patients with bilateral first molar extraction space and 8 molars from patients with unilateral first molar extraction space) where molar protraction was performed with no piezocesion

Late piezocision

Other

group 3 consisted of 21 molars (group 2 subjects where piezocession was carried on after 3 months of molar protraction with no piezocesion.

干预措施: Piezocision (Procedure)

结局指标

主要结局

Rate of second molar protraction

时间窗: up to 3 months

measured in mm/month from onscreen dental cast

Changes in the level of of Interleukin1-β

时间窗: Immediately before protraction/piezocision, 1 day, 1 week and 4 weeks after protraction/piezocision

detected in Gingival crevicular fluid (GCF)

次要结局

  • Pain Perception: Visual analogue scale (VAS)(Every day up to 7 days)
  • Anchorage loss(Each month up to 3 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Elham Abu Alhaija

Principal Investigator - Main thesis supervisor

Jordan University of Science and Technology

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