A clinical trial to study the effects of oolong tea as an adjunct to professional cleaning of teeth, in patients with mild to moderate gum and bone disease.

Phase 3

Completed

• Conditions: Health Condition 1: null- Mild to moderate chronic periodontitis

• Registration Number: CTRI/2017/02/007938
• Lead Sponsor: Manipal College of Dental Sciences Manipal

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2018-09-20
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

1) 20- 60 year old males and females

2) With mild to moderate periodontitis -

This selection is based according to American Academy of Periodontology (1999) : the classification of severity is as follows:

mild : 1-2 mm of clinical attachment loss

moderate : 3-4 mm of clinical attachment loss

severe : > 5 mm of clinical attachment loss

3) Presence of minimum of 20 teeth

Exclusion Criteria

1) Patient with any systemic diseases, severe liver or kidney disease, or severely ill patients with multiple drug requirements, patients with iron deficiency, anemia, anxiety, bleeding disorders, heart conditions, history of peptic ulcers.

2) Patients consuming any concurrent medications or those who have taken antibiotics or antiinflammatory medication in the past 6 months, similar products or mouthwashes.

3) Patient with any orthodontic or prosthodontic appliance

4) Patient with oral abusive habits such as smoking, alcohol intake and betel nut chewing or any other form of tobacco

5) Pregnant or lactating mothers

6) Patients who have undergone any periodontal treatment in the last 6 months

7) Patients with a high polyphenol diet (green tea, fish)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Glutathione peroxidase levels in saliva, gingival crevicular fluid and serum <br/ ><br>2. Malondialdehyde levels in saliva, gingival crevicular fluid and serum <br/ ><br>3. Total antioxidant levels in saliva, gingival crevicular fluid and serum <br/ ><br>Timepoint: Baseline <br/ ><br>1 month after start of study <br/ ><br>3 months after start of study

Secondary Outcome Measures

Name	Time	Method
1. Gingival index- Loe and Silness (1963) <br/ ><br>2. Plaque Index- Silness and Loe (1964) <br/ ><br>3. Probing pocket depth <br/ ><br>4. Clinical attachment loss <br/ ><br>5. % of sites with bleeding on probing. <br/ ><br>6. Lobene stain index <br/ ><br>7.The estimation of Colony Forming Units (C.F.U) will be done for selective supragingival plaque bacteria such as S. aureus, S. mutans, P. gingivalis, P. intermedia, F. nucleatum, S. salivarius and S. sanguisTimepoint: Baseline <br/ ><br>1 month after start of study <br/ ><br>3 months after start of study