Trial on effectiveness of omega 3 fatty acid supplements compared to Topical Steroids in Oral Lichen Planus Management

This study is a Randomized Control Trial to evaluate the Effectiveness of Omega-3 fatty acid supplements in the patients with Oral Lichen Planus.This is a hospital based study, conducting in the Department of Oral Medicine and Radiology, Kannur Dental College. The study duration will be 1 year. Patients in the age group of 18 years and above and clinically diagnosed Oral Lichen Planus  patients according to WHO 2003 criteria will be the inclusion criteria.Exclusion criteria include, the patients having HIV infection and other immuno compromised diseases. Patients on immune suppressant medication for other reasons, cancer chemotherapy, radiotherapy and pregnant and lactating women. All participants will be explained about the study and written informed consent will be obtained. Participants in the study will be randomly allocated using computer software program into intervention and control group , having 21 participants in each group. Group1 will be the control group with 21 participants they will be administered with Topical Corticosteroids and Group 2 will be the intervention group with 21 participants and they will be administered with Topical corticosteroids and 1000mg of Omega-3 fatty acid with 180mg EPA and 120mg DHA. Baseline measurements will be taken using the following outcome measures- VAS score and REU score. At every followup visits on 2nd, 4th, 8th and 12th week the same measures will be used to assess the outcome. Total duration will be 3 months.