MedPath

Diabetes and Eye

Not Applicable
Completed
Registration Number
CTRI/2018/05/014060
Lead Sponsor
ovartis Healthcare Pvt Ltd
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
30
Inclusion Criteria

Patients must be above 18 years of age having type 1 or type 2 diabetes mellitus. Decrease in vision specifically due to DME. Retinal thickness less than 300 micron and bilaterally fit cases.

Exclusion Criteria

Active intraocular inflammation, any active infection, history of uveitis, ocular disorders, epiretinal membrane, uncontrolled glaucoma, neovascularization of the iris, evidence of vitreomacular traction, active proliferative diabetic retinopathy.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Meanchange from baseline in BCVA assessed on early treatment diabetic retinopathy study (ETDRS) chart over a period of 48 weeks of Ranibizumab treatment in different morphological variants of Diabetic Macular Oedema.Timepoint: 12 Months
Secondary Outcome Measures
NameTimeMethod
Evaluate the mean change of BCVA on ETDRS after injection for 12 months on a monthly basis, evaluate the changes in intraretinal thickness and morphology in OCT; incidence and type of any clinical or lab adverse experiences.Timepoint: 12 Months
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