Fetal Heart Rate Variability
- Conditions
- Fetal Growth Retardation
- Interventions
- Diagnostic Test: fetal heart rate variability
- Registration Number
- NCT04323865
- Lead Sponsor
- University of Aarhus
- Brief Summary
Need statement
- a new way to distinguish between a healthy small fetus and a small fetus suffering from deprivation of nutrition and oxygen to prevent unnecessary induction of preterm birth and improve neonatal outcome.
Aim - to characterize fetal heart rate variability (fHRV) based on fetal ECG in the normal fetus and in the fetus suffering from growth retardation to evaluate its value and applicability as a supplementary tool in fetal surveillance.
Aim of current study
- To evaluate the feasibility of NI-FECG from gestational week 20 and onwards and investigate if important factors as length and heart rate pattern affects repeatability of time domain and spectral analyses in fetuses.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 75
• Healthy singleton pregnancies
• Fetal malformations, multiple pregnancy, obstetric complications, maternal chronic disease and labor.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Study 2. Repeatability of FHRV fetal heart rate variability -
- Primary Outcome Measures
Name Time Method Standard deviation of normal to normal RR-interval (SDNN) 01.04.2020 Time domain analysis, measured in ms
Root mean square of successive RR-interval differences (RMSSD) 01.04.2020 Time domain analysis, measured in ms
LF-power/HF-power 01.04.2020 Spectral analysis, ratio
Low frequency power (LF-power) 01.04.2020 Spectral analysis, measured in ms\^2
High frequency power (HF-power) 01.04.2020 Spectral analysis, measured in ms\^2
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Arhus Universityhospital
🇩🇰Aarhus, Aarhus N, Denmark