Anesthesia management of covid-19 associated ROC mucormycosis

Completed

Conditions: Coronavirus as the cause of diseases classified elsewhere,

Registration Number: CTRI/2022/01/039622

Lead Sponsor: Ashwini Yadavrao Sontakke

Brief Summary: After approval from the ethics committee and written informed consent, patients posted for emergency surgical resection of rhinoorbitocerebral mucormycosis under general anaesthesia satisfying inclusion and exclusion criteria for the study will be observed. intaoperative monitoring will include 3 lead electrocardiogram, heart rate, peripheral oxygen saturation, end tidal carbon dioxide concentration, non invasive blood pressure monitoring. patients, that will not have any intaoperative complications will be extubated in operative room before transfer to post-anaesthesia care unit or ward. however, patients undergoing extensive surgical resection, hemodynamic unstability are transferred to post anaesthesia care unit with endotracheal tube or tracheostomy tube in situ.

**Parameters to be noted :**

age

gender

BMI

systemic Illness

duration of Diabetes

COVID-19 status

vaccination

duration between COVID-19 and rhinoorbitocerebral symptoms

clinical staging of mucormycosis

duration between symptoms and surgery

Amphotericin -b days

pre-operative condition of patient

RT-PCR

ASA-PS grade

airway examination

anticoagulation/bedridden

steroids status

RS

CVS

spo2

RBS

Investigations

intra-operative- pulse/NIBP/

intubation

Ax maintenance

surgery performed

anaesthesia duration

surgery duration

complications

post-anaesthesia care unit

ventilatory support/inotropic support

total days of hospitalisation

total number of debridement

discharged/died

30 days outcome

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 50

Inclusion Criteria

All patients posted for emergency or elective surgical resection of rhiniorbitocerebral mucormycosis under general anaesthesia.

Exclusion Criteria

Lack of patients consent coagulopathy.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.Study the outcome of patients in following parameters	1.Before Surgery \| 2.Intraoperative \| 3.Immediate postoperative \| 4.Till discharge / Death \| 5.30 days
2.Mortality rate and average mortality time	1.Before Surgery \| 2.Intraoperative \| 3.Immediate postoperative \| 4.Till discharge / Death \| 5.30 days
Requirement of inotropic support, ventilator support, ICU stay, total duration of hospitalization, co-morbid condition affecting the outcome	1.Before Surgery \| 2.Intraoperative \| 3.Immediate postoperative \| 4.Till discharge / Death \| 5.30 days

Secondary Outcome Measures

Name	Time	Method
Early debidement of disease and outcome of patients.	5.co-relation between predisposing factors and outcome of patients

Trial Locations

Locations (1): Dr. Shankarrao Chavan Government Medical College and Hospital Vishnupuri Nanded
🇮🇳
Nanded, MAHARASHTRA, India
Dr. Shankarrao Chavan Government Medical College and Hospital Vishnupuri Nanded
🇮🇳Nanded, MAHARASHTRA, India
Dr Ashwini Yadavrao Sontakke
Principal investigator
8087330897
drsontakkeashwiniy@gmail.com