NCT02014428已完成4 期
Oral Low-molecular Weight Hyaluronic Acid in the Treatment of Atrophic Vaginitis
AGUNCO Obstetrics and Gynecology Centre1 个研究点 分布在 1 个国家开始时间: 2013年12月18日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 试验地点
- 1
- 主要终点
- Atrophic vaginal changes
研究概览
简要总结
To evaluate the effectiveness of low molecular weight hyaluronic acid oral tablets for the treatment of atrophic vaginitis.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 45 Years 至 65 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •at least 12 months postmenopausal
- •mucosal atrophy and the main bothersome related symptoms, such as itching, burning, and dyspareunia.
排除标准
- 未提供
研究组 & 干预措施
Hyaluronic acid
Experimental
220 mg hyaluronic acid per tablet (two tablets/day for 10 days, and subsequently one tablet/day for three months)
干预措施: Hyaluronic acid (Dietary Supplement)
Placebo
Placebo Comparator
two tablets/day for 10 days, and subsequently one tablet/day for three months
干预措施: Placebo (Drug)
结局指标
主要结局
Atrophic vaginal changes
时间窗: Change from baseline epithelium at 3 months
Morphometric analysis of biopsies.
次要结局
- Assessment of Dyspareunia(Change from baseline Dyspareunia at 3 months)
- Assessment of Itching(Change from baseline Itching at 3 months)
- Assessment of Burning(Change from baseline Burning at 3 months)
研究者
研究点 (1)
Loading locations...
相似试验
已完成
Unknown
Evaluation of oral hyaluronan effect for skin wrinkleskin wrinkleJPRN-jRCT1091220234Mariko Oe60
已完成
2 期
Hyaluronic Acid in Acute Exacerbation of COPD - Duration Of Noninvasive AssistanceChronic Obstructive Pulmonary DiseaseNCT02674880Campus Bio-Medico University41
已完成
不适用
Effectiveness of Oral Hyaluronic Acid (A+ HA(tm), TOP Pharm.) in Knee Osteoarthritis: Clinical TrialKnee OsteoarthritisNCT04212741China Medical University Hospital97
已完成
不适用
Effect of a Combination of Hyaluronic Acid, Chondroitin Sulphate and Magnesium Trisilicate on Subjects With GastroEsophageal Reflux DiseaseGastro Esophageal RefluxNCT03883074SOFAR S.p.A.21
已完成
不适用
Effectiveness of Oral Hyaluronic Acid in Knee OsteoarthritisKnee OsteoarthritisNCT04352322China Medical University Hospital47