Comparison of Ultrasound-guided Quadratus Lumborum Block and Iliohypogastric/Ilioinguinal Nerve Block for Postoperative Pain Management in Patients Undergoing Cesarean Section

Not Applicable

• Conditions: Cesarean Section; Quadratus Lumborum Block; Iliohypogastric/Ilioinguinal Nerve Block
• Interventions: Procedure: iliohypogastric/ilioinguinal nerve block; Procedure: quadratus lumborum block; Procedure: epidural analgesia

• Registration Number: NCT04822870
• Lead Sponsor: Peking University People's Hospital

Brief Summary

The purpose of this study is to compare the analgesic effect of ultrasound-guided quadratus lumborum block and iliohypogastric/ilioinguinal nerve block for postoperative pain management in patients undergoing cesarean section.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-03-17
• Study First Submitted QC: 2021-03-29
• Study First Posted: 2021-03-30
• Study Start: 2021-03-31
• Status Verified: 2021-04
• Last Update Submitted: 2021-04-02
• Last Update Posted: 2021-04-06
• Primary Completion: 2021-05
• Study Completion: 2021-05

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 87

Inclusion Criteria

• singleton pregnancy
• gestation of at least 37 weeks
• American Society of Anesthesiologists (ASA) physical status I or II
• finish Pfannenstiel section under combined spinal and epidural anesthesia

Exclusion Criteria

• pruritus existed before the surgery
• allergic to lidocaine, ropivacaine or dexamethasone

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
iliohypogastric/ilioinguinal nerve block	iliohypogastric/ilioinguinal nerve block	Parturients receive ultrasound-guided iliohypogastric/ilioinguinal nerve block as post-operative analgesia.
quadratus lumborum block	quadratus lumborum block	Parturients receive ultrasound-guided quadratus lumborum block as post-operative analgesia.
epidural analgesia	epidural analgesia	Parturients receive epidural morphine via epidural catheter placed during anesthesia as post-operative analgesia.

Primary Outcome Measures

Name	Time	Method
morphine consumption	24 hours postoperatively	Every parturient use a patient-controlled intravenous analgesia pump as supplement for the interventions. The analgesia pump contains morphine and can record morphine consumption. Postoperative use of morphine can reflect analgesic effect.

Secondary Outcome Measures

Name	Time	Method
morphine consumption	48 hours postoperatively	Every parturient use a patient-controlled intravenous analgesia pump as supplement for the interventions. The analgesia pump contains morphine and can record morphine consumption. Postoperative use of morphine can reflect analgesic effect.
effective analgesia time	48 hours postoperatively	Time period between finish the intervention and the first time parturient use the patient-controlled intravenous analgesia pump for analgesia supplement.
satisfaction score	48 hours postoperatively	Ask the patient to evaluate satisfaction score using 0-10. 0 refers totally dissatisfied, 10 refers to the most satisfied
hospital stay	at discharge assessed up to 10 days	The hospitalize length
pain score	48 hours postoperatively	Use visual analogue scale (VAS) 0-10 to evaluate pain intensity and reflect analgesic effect. 0 refers to completely no pain, 10 refers to the most severe pain she has experienced.
adverse effect	48 hours postoperatively	Nausea and vomiting, pruritus, oversedation, respiratory depression and urinary retention are considered adverse effects. The incidence and severity are recorded, 1 score refers to mild, 2 scores refers to moderate, 3 scores refers to severe and treatment needed.
hospitalize cost	at discharge assessed up to 10 days	Total cost in this hospitalization

Trial Locations

Locations (1)

Peking University People's Hospital; 🇨🇳 Beijing, Beijing, China