Management of Smoking in primary Care: A randomised controlled trial on the effectiveness of GP/nurse promotion of e-cigarettes in supporting reduced smoking and abstinence in hardcore smokers with smoking-related chronic disease

niversity of Oxford0 个研究点目标入组 325 人开始时间: 2017年11月28日最近更新: 2024年1月22日

试验速览

2019 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/31779689 protocol (added 02/12/2019)

•1. Participant is willing and able to give informed consent for participation in the study
•2. Aged 18 years or above
•3. Current smoker with a value of at least 10 parts per million (ppm) for exhaled carbon monoxide (CO)
•4. Diagnosed with one or more of the following chronic conditions: ischaemic heart disease, peripheral vascular disease, hypertension, diabetes mellitus (Type 1 and Type 2), stroke, asthma, COPD, chronic kidney disease, depression, schizophrenia, bipolar disorder or other psychoses

•1. GP believes that switching to e-cigarettes would not benefit the patient given their current medical condition
•2. Currently using e-cigarettes, nicotine replacement therapy or non-nicotine based cessation therapies (e.g. bupropion, nortriptyline or varenicline)
•3. Plans to stop smoking before or at the annual review
•4. Currently enrolled in another smoking-related study or other study where the aims of the studies are incompatible
•5. Cannot consent due to mental incapacity
•6. Pregnant, breastfeeding or planning to become pregnant during the course of the study

发起方