Research on the Evolution, Geometry, and Alterations of the Periorbital Region Based on Age and Deformations

Not Applicable

Not yet recruiting

• Conditions: Facial Skin; Motion Capture; Aging; Periorbital Region; Skin Movement; Vertical Jump

• Registration Number: NCT07080320
• Lead Sponsor: Centre Hospitalier Universitaire, Amiens

Brief Summary

The periorbital region of the face is a critical area affected by aging. Motion Capture (MoCap) allows the precise measurement of the mechanical properties of skin in this region. This study will validate MoCap as a tool for quantifying these properties, comparing it to traditional reference tools, and exploring how these properties evolve with age and external treatments. It will also assess MoCap's ability to detect the effects of various treatments such as tightening products and massages. Ultimately, this research will provide a deeper understanding of skin dynamics in the periorbital region and offer insights into both medical and cosmetic applications.

Detailed Description

Not available

Study Timeline

• Status Verified: 2025-07
• Study First Submitted: 2025-07-15
• Study First Submitted QC: 2025-07-15
• Last Update Submitted: 2025-07-15
• Study First Posted: 2025-07-23
• Last Update Posted: 2025-07-23
• Study Start: 2025-08-01
• Primary Completion: 2027-08
• Study Completion: 2027-09-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Female participants
• Caucasian, Fitzpatrick skin types I-III
• BMI between 18.5 and 27, healthy participants
• Aged 18 to 65 years (inclusive)
• Not under guardianship or curatorship
• Informed written consent
• Social security affiliation
• Non-smokers for at least 5 years
• No excessive UV exposure (artificial or natural) in the last 3 weeks prior to the study or during the study

Exclusion Criteria

• Severe skin disorders preventing the application of electrodes or photo-reflective markers
• Neurovascular history affecting the face
• Ongoing treatments influencing facial tissues (e.g., corticosteroids)
• Current sleep disorders
• Psychiatric conditions or social interaction impairments
• Inner ear or balance disorders
• Osteoporosis, recent fractures, or fragile bone conditions
• Pregnant or breastfeeding women
• Under guardianship, curatorship, or legal protection

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
maximum displacement (in millimeters) of each marker placed on the face	day 1	maximum displacement (in millimeters) of each marker placed on the face during standardized movements of the periorbital region

Secondary Outcome Measures

Name	Time	Method
Coefficient of variation of the maximum displacement amplitudes measured during repeated tests for the same movement.	day 1
The correlation coefficient between dynamic MoCap measurements and static measurements obtained from reference tools.	day 1	The correlation coefficient between dynamic MoCap measurements and static measurements obtained from reference tools.
The difference in the mean maximum displacement amplitudes (in millimeters) between different age groups	day 1	The difference in the mean maximum displacement amplitudes (in millimeters) between different age groups
The difference in the mean maximum displacement amplitudes (in millimeters) before and after performing a periorbital massage	day 1	The difference in the mean maximum displacement amplitudes (in millimeters) before and after performing a periorbital massage
The maximum mean displacement amplitudes (in millimeters) during a mechanical solicitation (a standardized vertical jump).	day 1	The maximum mean displacement amplitudes (in millimeters) during a mechanical solicitation (a standardized vertical jump).
The difference in the mean maximum displacement amplitudes (in millimeters) before and after applying a tightening product (aloe vera).	day 1	The difference in the mean maximum displacement amplitudes (in millimeters) before and after applying a tightening product (aloe vera).

Trial Locations

Locations (1)

CHRU Amiens; 🇫🇷 Amiens, France