Surface Treatment of the Dental Implant on the Osseointegration

Not Applicable

Completed

• Conditions: Dental Implants; Surface Treatment
• Interventions: Other: Neoporous alvim CM, neodent implant (Control); Other: Aqua alvim CM, neodent implant (Test)

• Registration Number: NCT05194813
• Lead Sponsor: Hams Hamed Abdelrahman

Brief Summary

Dental implants have become a widely accepted treatment modality for the replacement of missing single or multiple teeth in the recent years. In order to meet patients' needs for shorter treatment times and the necessity of dealing with more challenging clinical situations, implants and implant therapies have undergone continuous improvement to improve the function and longevity of the implants. Recently the constant search for improvements in modern implant have been focused on surface modifications so a new era of surface treatment have been showed up; the chemically modified hydrophilic surfaces.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-11-01
• Primary Completion: 2021-06-15
• Study Completion: 2021-06-15
• Status Verified: 2022-01
• Study First Submitted: 2022-01-04
• Study First Submitted QC: 2022-01-04
• Last Update Submitted: 2022-01-04
• Study First Posted: 2022-01-18
• Last Update Posted: 2022-01-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

• Missing mandibular posterior teeth.
• Good oral hygiene (plaque index less than 10 %)
• Good compliance to the treatment.
• Participants are free from local or systemic disease
• Willingness and ability to commit to follow-up placement.
• Adequate bone height and width to accommodate implant placement and sufficient keratinzed mucosa.
• At least 3months after tooth extraction
• Sufficient interocclusal distance

Exclusion criteria

• Presence of persistent and unresolved infection in the implant site
• Parafunctional habits.
• Heavy Smokers.
• Uncontrolled systemic disease that impedes bone healing

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Conventional hydrophobic sandblasted and acid-etched dental implant	Neoporous alvim CM, neodent implant (Control)	-
Hydrophilic sandblasted and acid-etched dental implants	Aqua alvim CM, neodent implant (Test)	-

Primary Outcome Measures

Name	Time	Method
Change in implant stability	at baseline and 6 months	The implant stability measurement was examined at the time of insertion of the implants (primary stability) and 6 months (secondary stability) for the two groups of patients using the resonance Frequency Analysis (RFA) via the Osstell ISQ system
Biochemical assessment of bone formation	at 3 months	Done by measuring of Runt-related transcription factor 2 (RUNX2) as a bone marker by Enzyme-Linked Immunosorbent Assay
Change in bone density	at baseline and 6 months	Cone beam Computerized tomography was used to assess bone denisty
Change in ridge height	at baseline and 6 months	Cone beam Computerized tomography was used to assess ridge height

Trial Locations

Locations (1)

Alexandria Faculty of Dentistry; 🇪🇬 Alexandria, Egypt