The Effect of Surface Treatment of the Dental Implant on the Osseointegration in Mandibular Posterior Missing Teeth
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 16
- 试验地点
- 1
- 主要终点
- Change in implant stability
研究概览
简要总结
Dental implants have become a widely accepted treatment modality for the replacement of missing single or multiple teeth in the recent years. In order to meet patients' needs for shorter treatment times and the necessity of dealing with more challenging clinical situations, implants and implant therapies have undergone continuous improvement to improve the function and longevity of the implants. Recently the constant search for improvements in modern implant have been focused on surface modifications so a new era of surface treatment have been showed up; the chemically modified hydrophilic surfaces.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Missing mandibular posterior teeth.
- •Good oral hygiene (plaque index less than 10 %)
- •Good compliance to the treatment.
- •Participants are free from local or systemic disease
- •Willingness and ability to commit to follow-up placement.
- •Adequate bone height and width to accommodate implant placement and sufficient keratinzed mucosa.
- •At least 3months after tooth extraction
- •Sufficient interocclusal distance
- •Exclusion criteria
- •Presence of persistent and unresolved infection in the implant site
- •Parafunctional habits.
- •Heavy Smokers.
- •Uncontrolled systemic disease that impedes bone healing
排除标准
- 未提供
结局指标
主要结局
Change in implant stability
时间窗: at baseline and 6 months
The implant stability measurement was examined at the time of insertion of the implants (primary stability) and 6 months (secondary stability) for the two groups of patients using the resonance Frequency Analysis (RFA) via the Osstell ISQ system
Biochemical assessment of bone formation
时间窗: at 3 months
Done by measuring of Runt-related transcription factor 2 (RUNX2) as a bone marker by Enzyme-Linked Immunosorbent Assay
Change in bone density
时间窗: at baseline and 6 months
Cone beam Computerized tomography was used to assess bone denisty
Change in ridge height
时间窗: at baseline and 6 months
Cone beam Computerized tomography was used to assess ridge height
次要结局
未报告次要终点
研究者
Hams Hamed Abdelrahman
Assistant lecturer of DPH and Clinical statistician
Alexandria University