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Clinical Trials/NCT05194813
NCT05194813
Completed
Not Applicable

The Effect of Surface Treatment of the Dental Implant on the Osseointegration in Mandibular Posterior Missing Teeth

Hams Hamed Abdelrahman1 site in 1 country16 target enrollmentNovember 1, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Dental Implants
Sponsor
Hams Hamed Abdelrahman
Enrollment
16
Locations
1
Primary Endpoint
Change in implant stability
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

Dental implants have become a widely accepted treatment modality for the replacement of missing single or multiple teeth in the recent years. In order to meet patients' needs for shorter treatment times and the necessity of dealing with more challenging clinical situations, implants and implant therapies have undergone continuous improvement to improve the function and longevity of the implants. Recently the constant search for improvements in modern implant have been focused on surface modifications so a new era of surface treatment have been showed up; the chemically modified hydrophilic surfaces.

Registry
clinicaltrials.gov
Start Date
November 1, 2020
End Date
June 15, 2021
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Hams Hamed Abdelrahman
Responsible Party
Sponsor Investigator
Principal Investigator

Hams Hamed Abdelrahman

Assistant lecturer of DPH and Clinical statistician

Alexandria University

Eligibility Criteria

Inclusion Criteria

  • Missing mandibular posterior teeth.
  • Good oral hygiene (plaque index less than 10 %)
  • Good compliance to the treatment.
  • Participants are free from local or systemic disease
  • Willingness and ability to commit to follow-up placement.
  • Adequate bone height and width to accommodate implant placement and sufficient keratinzed mucosa.
  • At least 3months after tooth extraction
  • Sufficient interocclusal distance
  • Exclusion criteria
  • Presence of persistent and unresolved infection in the implant site

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Change in implant stability

Time Frame: at baseline and 6 months

The implant stability measurement was examined at the time of insertion of the implants (primary stability) and 6 months (secondary stability) for the two groups of patients using the resonance Frequency Analysis (RFA) via the Osstell ISQ system

Biochemical assessment of bone formation

Time Frame: at 3 months

Done by measuring of Runt-related transcription factor 2 (RUNX2) as a bone marker by Enzyme-Linked Immunosorbent Assay

Change in bone density

Time Frame: at baseline and 6 months

Cone beam Computerized tomography was used to assess bone denisty

Change in ridge height

Time Frame: at baseline and 6 months

Cone beam Computerized tomography was used to assess ridge height

Study Sites (1)

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