The effect of two different fats (medium chain triglycerides and long chain triglycerides) combined with exercise on energy balance

Not Applicable

Completed

• Conditions: Energy balance; Nutritional, Metabolic, Endocrine

• Registration Number: ISRCTN15611082
• Lead Sponsor: Oxford Brookes University

Brief Summary

2019 results in https://pubmed.ncbi.nlm.nih.gov/31690357/ (added 03/06/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-04-19
• Study Completion: 2017-06-01
• Last Update Posted: 15 June 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 12

Inclusion Criteria

1. Aged 18-65
2. Male
3. BMI of 18.5-29.9 kg/m2

Exclusion Criteria

1. Allergic/intolerant to any of the foods provided in the study
2. Taking medication which could affect appetite
3. Smokers
4. A ‘restrained eater’, as defined by the TFEQ and DEBQ
5. Not weight stable (losing/gaining 3kg in the last 3 months)
6. Currently dieting to lose weight

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> 1. Energy intake, assessed by the ad libitum buffet lunch that participants consume at the end of trials in the lab at 255–285 mins<br> 2. Subjective sensations of appetite (hunger, fullness, desire to eat, prospective food consumption and nausea), measured using Visual Analogue Scales at 0 mins, 10 mins, 30 mins, 60 mins, 90 mins, 120 mins, 180 mins, 210 mins, 240 mins and 285 mins<br> 3. Energy balance, measured using the CPX Ultima and combined with energy intake data, at -30 mins – 0 mins, 30 mins – 45 mins, 60 mins – 75 mins, 90 mins – 105 mins, 120 mins – 180 mins, 210 mins – 225 mins, 240 mins – 255 mins<br>

Secondary Outcome Measures

Name	Time	Method
<br> 1. 24 hour energy intake, measured using recorded diet diaries completed after the morning in the lab<br> 2. Gastrointestinal distress (to identify any adverse effects associated with the lipids), measured using a GI Distress questionnaire on the morning following the lab visit<br> 3. Gastric emptying, measured through the 13C octanoic acid breath test at 0 min, 15 min, 30 min, 45 min, 60 min, 75 min, 90 min, 105 min, 120 min, 135 min, 150 min, 165 min, 180 min, 195 min, 210 min, 225 min, 240 min, 285 min<br> 4. Hedonic properties of the lipid (to outline palatability issues with the breakfasts which may confound the results), assessed by Quantitative Descriptive Analysis at 10 min<br>