The Relevance of Biochemical Markers in the Process of Weaning
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Duration of Weaning
- Sponsor
- Heidelberg University
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- success of weaning
- Last Updated
- 15 years ago
Overview
Brief Summary
The purpose of the study is to examine the relevance of biochemical markers (specific pulmonary and cardiac markers and markers of endogenous stress) in the process of weaning in patients with artificial ventilation.
Detailed Description
Artificially ventilated patients on our intensive care unit will be monitored if specific biomarkers have a relevance in risk stratification, optimizing therapy, outcome and success in the process of weaning. Therefore, consecutively, specific blood parameters will be taken at time of intubation,day 1 of weaning and extubation.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Written informed consent
- •Able and willing to understand the protocol
- •At least 18 years or older
Exclusion Criteria
- •Not fulfilling inclusion criteria
Outcomes
Primary Outcomes
success of weaning
Time Frame: participants will be followed for the duration of hospital stay, an expected average of 30days
primary outcome measure is the success of weaning during hospital stay. Duration of hospital stay is estimated between 1-60days, in average 30days. Criteria is spontaneous breathing.
Secondary Outcomes
- follow up(12 months)