Efficacy and safety of cold polypectomy for nonampullary duodenal adenomatous lesion - Cold polypectomy for nonampullary duodenal adenoma

Overall, 39 lesions in 30 patients were removed via cold polypectomy (CFP, 9 lesions in 8 patients; CSP, 30 lesions in 22 patients). Seven of 9 (77.8%) and 29 of 30 (96.7%) lesions were removed en bloc via CFP and CSP, respectively. Pathologically, 34 of the 39 lesions (87.2%) were confirmed as adenomas, and their mean size was 3.9+-1.2mm (range 2-6mm). Of the 34 adenomas, 20 (58.8%) were R0 resection lesions, of which 3 of 9 (33.3%) and 17 of 25 (68.0%) had undergone CFP and CSP, respectively. No delayed bleeding or intraprocedural/delayed perforation was observed. All 30 patients with the 34 pathologically confirmed adenomas underwent upper gastrointestinal endoscopy 3 months after cold polypectomy, and no morphological or pathological recurrence was identified.