Follow-up of patients with chronic nodular prurigo

• Conditions: L28.1; L28.2; Prurigo nodularis; Other prurigo

• Registration Number: DRKS00022555
• Lead Sponsor: Department of Dermatology and Center for Chronic Pruritus

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-10-07
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Diagnosis: chronic nodular prurigo (L28.1/L28.2)
- Participation in the PRISM trial completed (study arm 1)
- Study-naive patients (study arm 2)
- NRS >3 (study arm 2)
- 18 years of age or older

Exclusion Criteria

- No understanding of the German language

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
- Stage and activity of the prurigo skin lesions (IGA-CPG stage score, IGA-CPG activity score), as well as dynamics of the skin lesions (no change, improved, deteriorated)<br>- Pruritus intensity (worst pruritus intensity of the last 24 hours on the NRS, average pruritus intensity of the last 24 hours on the NRS, worst pruritus intensity of the last 4 weeks on the NRS), and dynamics of the pruritus intensity (dynamic pruritus score).

Secondary Outcome Measures

Name	Time	Method
- Demographic data (age, sex, height, weight)<br>- General data (family status, employment, education)<br>- Medical history (cause underlying prurigo, atopy, comorbidities, medication)<br>- Current and prior therapy of prurigo