Effect of pre-conceptional ayurvedic protocol in the management of recurrent pregnancy loss in first trimester: a single arm open labelled clinical study

INTRODUCTION

Recurrent pregnancy loss (RPL), also referred to as recurrent miscarriage or habitual abortion, is 2 or more consecutive pregnancy losses prior to 20 weeks from the last menstrual period. The incidence of RPL is increasing and its management is quite varied and challenging.  Management of RPL has to be revised as it requires intervention from Pre-conceptional period itself. Ayurveda gives great importance for the preconception care & Garbhini Paricharya, to ensure a healthy and successful progeny. The present protocol is selected ensuring both Shodhana and Shamana action through Virechana, Matra Basti, Uttara Basti and internal medication.

MATERIALS AND METHODS

In the present study, minimum 15 diagnosed patients of RPL fulfilling the selection criteria will be registered. Single group of the patients will be treated. In the first cycle *Deepana Pachana,*Snehapana, Sarvanga Abhyanga & Swedana and Virechana Karma will be performed. In the second cycle Matra Basti with Sahacharadi Taila and Uttara Basti with Kashmari Kutaja Siddha Ghrutha in the third cycle will be performed. Prajasthapana Churna will be given orally in 2nd& 3rd menstrual cycles after the  completion of Basti in both cycles.

RESULTS AND DISCUSSION

Data generated during the above study will be presented in a systemic methodical manner as shall be analysed and the section where the important points of the Conceptual study, Clinical study, Pharmacological study will be discussed.

FOLLOW UP

Patients will be advised to visit the hospital weekly during treatment. Follow up will be done every 15 days for 2 months after the completion of intervention in every patient. If the patient conceives, follow up will be done for 3 months (during first trimester of pregnancy). After the conception routine Garbhini Paricharya as advised in regular  PTSR OPD including checkups, medicines (Bala+Shatavari +Guduchi +Brahmi +Nagkeshara each 1gm morning –evening before food with luke warm milk) USG and laboratory tests will be advised.

SIDE EFFECTS

These drugs have no known unwanted effects. It is possible that it may also cause some problems that we are not aware of. Adverse Drug Reaction if any observed will be reported to the Pharmacovigilance cell of I.T.R.A., Jamnagar.