Post-operative Urinary Retention: A Prospective Randomized Study Identifying Patients at Risk and Reducing the Incidence Using Tamsulosin Pretreatment
试验速览
- 阶段
- 4 期
- 入组人数
- 140
- 试验地点
- 1
- 主要终点
- Post-operative urinary retention
研究概览
简要总结
Investigating whether pre-operative treatment with a selective alpha1-adrenoceptor antagonist affects the likelihood of male patients developing post-operative urinary retention following hernia repair.
详细描述
The purpose of this study will be to investigate whether pre-operative treatment with a selective alpha1-adrenoceptor antagonist affects the likelihood of male patients developing post-operative urinary retention following hernia repair surgery. It is also of interest to determine whether or not a well-known urological screening tool, the IPSS, can identify patients at risk for urinary retention following elective laparoscopic or open hernia repair surgery. We will investigate if it is possible to pre-treat patients with a selective alpha1-adrenoceptor antagonist which we think can reduce the incidence of post-operative urinary retention and the associated adverse consequences, especially in those patients at higher risk.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •18 years of age
- •Presenting with hernia requiring surgical intervention
排除标准
- •Intolerability of tamsulosin or related drugs
- •Investigator discretion
- •Unwillingness or inability to comply with protocol procedures and assessments
研究组 & 干预措施
Treatment
treatment with a selective alpha1-adrenoceptor antagonist
干预措施: Tamsulosin (Drug)
结局指标
主要结局
Post-operative urinary retention
时间窗: 2 weeks
Incidence of post-operative urinary retention in patients undergoing hernia repair
次要结局
- Effect of IPSS(2 weeks)