Invasive Candidiasis in Critically Ill Patients in Saudi Arabia: A Prospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 162
- 试验地点
- 2
- 主要终点
- Hospital Mortality
研究概览
简要总结
Epidemiology and clinical outcomes of invasive candidiasis in critically ill patients in Saudi Arabia is not well studied. This observational study objectives include to determine the epidemiology, risk factors and outcomes of invasive Candida infection in critically ill patients in Saudi Arabia.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adult patients (> 18 years)
- •develop invasive candidiasis as per prespecified definitions during ICU stay
- •In addition, patients who had invasive candidiasis within 72 hours of ICU admission will be included
排除标准
- •Diagnosis of invasive candidiasis (definite or probable) more than 72 hours before ICU admission.
- •Diagnosis of invasive candidiasis (definite or probable) within 72 hours of ICU admission, but the admission to ICU for an unrelated reason.
- •Readmission to the ICU during the same hospitalization with invasive candidiasis occurring during one of the previous admissions.
结局指标
主要结局
Hospital Mortality
时间窗: Patients will be followed while in the ICU and the vital status at the time of discharge from the ICU will be noted. The expected stay in the ICU is 10 days on average.
For patients staying in the ICU for long periods, hospital mortality will be censored at 180 days after entry into the study.That is patient staying alive in the hospital more than 180 days will be considered alive.
次要结局
- ICU Mortality(patients will be followed until discharge from the hospital and vital status at discharge from the hospital will be noted (expected hospital stay is 5 weeks). Hopsital mortality will be censored at 180 days after entry into the study.)
- Length of Stay in the ICU(date of discharge from ICU minus date of admission to ICU)
- Duration of Mechanical Ventilation(date of extubtation minus date of intubation)
- Length of Stay in the Hospital(date of discharge from hospital minus date of admission to hospital)
研究者
Hasan Al-Dorzi
Consultant, Intensive Care Department
King Abdulaziz Medical City