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Effect of St. John`s wort on the pharmacokinetics and pharmacodynamics of oral oxycodone: A two-phase double-blind cross-over study in healthy volunteers /Mäkikuisman vaikutus suun kautta annetun oksikodonin farmakokinetiikkaan ja dynamiikkaan: kaksivaiheinen kaksoissokea vaihtovuoroinen tutkimus terveillä koehenkilöillä

Conditions
Drug interaction study
Registration Number
EUCTR2007-006135-32-FI
Lead Sponsor
Klaus Tapio Olkkola
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

Healthy, 18-40 years, nonsmoking, without chronic diseases or medication
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years)
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years)
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Medication, chronic diseases, abnormal laboratory tests, abuse problems

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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