National, Multicenter, Prospective Study of Screening of Fabry Disease in a Population of Men Over 28 Days Old and Less Than 55 Years, Hospitalized for an Ischemic Stroke.

University Hospital, Clermont-Ferrand1 site in 1 country889 target enrollmentMarch 2007

ConditionsIschemic Stroke Hospitalized

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Ischemic Stroke Hospitalized
Sponsor: University Hospital, Clermont-Ferrand
Enrollment: 889
Locations: 1
Primary Endpoint: Fabry disease's screening (Positive microdosage confirmed by a macrodosage)
Status: Completed
Last Updated: 16 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Fabry disease is a genetic disease due to an enzymatic deficit. A screening of this disease allows patients to benefit from an enzyme replacement therapy and prevent the occurrence of life threatening manifestations such as an ischemic stroke.

The purpose of the study is to determinate the prevalence of Fabry disease in a population of male patients hospitalized for an ischemic stroke.

This study, with a screening of Fabry disease, allows the patients to make a precise diagnosis of their ischemic stroke and to facilitate the screening of the other members at the facility.

Registry

clinicaltrials.gov

Start Date

March 2007

End Date

December 2009

Last Updated

16 years ago

Study Type

Interventional

Study Design

Single Group

Sex

Male

Investigators

Sponsor

University Hospital, Clermont-Ferrand

Eligibility Criteria

Inclusion Criteria

•Hospitalized ischemic stroke
•Written and signed informed consent from patient or legal representative

Exclusion Criteria

•Patients belonging to a family which has a Fabry disease's diagnosis confirmed

Outcomes

Primary Outcomes

Fabry disease's screening (Positive microdosage confirmed by a macrodosage)

Time Frame: Positive microdosage confirmed by a macrodosage

Secondary Outcomes

Describe and compare the characteristics of patients affected by Fabry disease and patients who are not affected Identify clinical and neuroradiological predictive elements of Fabry disease(patients affected by Fabry disease)