NCT01071525Unknown3 期
The Effect of Niacin Administration on Oxidative Stress in Patients With Hypercholesterolmia, as Measured by the Use of a Novel Biomarker
适应症
干预措施
相关药物
试验速览
- 阶段
- 3 期
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Effect on oxidative stress
研究概览
简要总结
- Treatment of Hypercholesterolemic patients with niacin will cause a significant decrease in oxidative stress and a decrease in the atherogenecity in blood samples of the patients.
- A possible correlation between oxidative stress in hypercholesterolemic patients taking niacin to clinical hypercholesterolemia parameters is possible.
- Using a novel biomarker will enable a precise detection of the change in the oxidative stress in hypercholesterolemic patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Hypercholesterolemia,
- •age above eighteen
排除标准
- •Treatment with fibrates,
- •Pregnant/Breast feeding women
研究组 & 干预措施
Niacin
Active Comparator
Hypercholesterolemic patients with high-density lipoprotein (HDL) less than 40 mg% will receive Niacin\Laropiprant.
干预措施: Niacin\Laropiprant (Drug)
Control
No Intervention
Maching subjects will receive no medication, Blood tests will be drawn for laboratory tests.
干预措施: Niacin\Laropiprant (Drug)
结局指标
主要结局
Effect on oxidative stress
时间窗: three months
次要结局
未报告次要终点
研究者
研究点 (1)
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