JPRN-UMIN000021069Completed未知
Placebo-controlled double-blinded parallel randomized study to test the urate-lowering effect of yogurt containing Lactobacillus gasseri PA-3 in adult males with marginal hyperuricemia - A study on the effect of the yogurt containing Lactobacillus gasseri PA-3 on uric acid level.
Tsukuba International Clinical Pharmacology Clinic0 sites60 target enrollmentStarted: February 17, 2016Last updated:
Conditions
Trial Snapshot
- Phase
- 未知
- Status
- Completed
- Sponsor
- Enrollment
- 60
Study Overview
Brief Summary
The results of the analysis after excluding the data with purine intake of over 450 mg/day have shown that serum urate of the high-concentration group was significantly lower than the placebo group at week 2 (P = 0.025), and the linear regression analysis has indicated a dose-dependent decrease of serum urate ( P = 0.046). The equivalent analysis using the data at week 8 also showed that serum urate of the high-concentration group was significantly lower than the placebo group (P = 0.031), and the linear regression analysis indicated a dose-dependent decrease of serum urate ( P = 0.021). Those data suggest that yogurt containing L. gasseri PA-3 lower serum urate.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 35years-old to ot applicable (—)
- Sex
- Male
Inclusion Criteria
- Not provided
Exclusion Criteria
- •1.Subjects with Phamacotherapy,Exercise therapy and Medical diet of hyperuricemia(gout). 2.Subjects with a history of gout or hyperuricemia. 3.Subjects with a using healthy food about hyperuricemia commonly. 4.Subjects who are judged ineligible by the principal investigator or subinvestigator.
Investigators
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