NCT02108457已完成不适用
[18F] Flourothymidine (FLT) PET/CT Imaging for Gynecologic Cancers
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 15
- 试验地点
- 1
- 主要终点
- Patients With Changes in Bone Marrow Assessed Through Images
研究概览
简要总结
The purpose of this study is to determine the effect of specific bone marrow maps developed with18F-FLT PET/CT imaging on the ability to spare proliferating bone marrow using proton beam radiotherapy compared to IMRT. Participants will be 18 years of age or old with a history of gynecologic cancer. Subjects will undergo 3 FLT-PET scans (one before treatment, one during the course of RT, and one 2-5 weeks after initiation of RT). Scans will take place in the Department of Radiation Oncology.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Participants will be 18 years of age or older
- •History of gynecologic cancer.
- •Recommended to undergo IMRT or PBT of the pelvis with concurrent chemotherapy
- •Female participants of child-bearing potential must have a negative urine or serum pregnancy test at the time of the screening visit.
- •Participants must be informed of the investigational nature of this study and provide written informed consent in accordance with institutional and federal guidelines prior to study specific procedures.
- •Participants must be willing and able to comply with scheduled visits and imaging procedures in the opinion of the investigator or treating physician.
- •Exclusion Criteria
- •Females who are pregnant or breast feeding at the time of screening will not be eligible for this study.
- •Inability to tolerate imaging procedures in the opinion of the investigator or treating physician
- •Serious or unstable medical or psychological conditions that, in the opinion of the investigator would compromise the subjects safety or successful participation in the study.
- •Unwilling or unable to provide informed consent
排除标准
- 未提供
结局指标
主要结局
Patients With Changes in Bone Marrow Assessed Through Images
时间窗: up to 5 weeks
次要结局
未报告次要终点
研究者
研究点 (1)
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