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临床试验/NCT06187844
NCT06187844尚未招募不适用

Value of Inguinal Exploration in Cases of Impalpable Testis With Cord Structures Entering the Inguinal Canal

Assiut University0 个研究点目标入组 50 人开始时间: 2024年2月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
尚未招募
入组人数
50
主要终点
. Percentage of positive inguinal exploration even by finding a testis or nubbin

研究概览

简要总结

  • To determine the percentage of children with impalpable testis who benefit from inguinal exploration after laparoscopic identification of cord structures entering the inguinal canal.
  • To determine the factors predicting the presence of inguinal testis in the previously mentioned children.

详细描述

The undescended testis represents one of the most common disorders of childhood. The most useful classification of undescended testes is distinguishing palpable and non-palpable tests, and the location and presence of the tests decide clinical management. Approximately 80% of all undescended tests are palpable and the other 20% are impalpable. Among the 20% of non-palpable testes, 50-60% are intra-abdominal, canalicular, or peeping (right inside the internal inguinal ring). The remaining 20% are absent and 30% are atrophic or rudimentary.

Diagnostic laparoscopy is the most useful modality for assessing nonpalpable testicles. The four most important structures to identify at laparoscopy are the testis, the testicular vessels, the vase deferens, and the patency of the processus vaginalis. The possible anatomical findings include spermatic vessels entering the inguinal canal (40%), an intra-abdominal (40%) or peeping (10%) testis, or blind-ending spermatic vessels confirming vanishing testis (10%). It permits the identification of three surgical scenarios that will lead to different courses of action:

  1. Blind-ending vessels, which indicate a vanishing intra-abdominal testis, and no further exploration is necessary (10%)
  2. Testicular vessels and vas entering the inguinal canal through the internal inguinal ring (34%).Inguinal exploration may find a testicular nubbin either in the inguinal region or in the scrotum, which may or may not be removed; or a healthy, palpable, undescended testicle amenable to standard orchidopexy.
  3. Peeping (11%) or intra-abdominal tests (37%), which will require either an open or a laparoscopic approach. Although Rozanski et al. reported the first case of intratubular germ cell neoplasia originating from a testicular remnant, the necessity of removing nubbins is controversial.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
6 Months 至 12 Years(Child)
性别
Male
接受健康志愿者
是

入选标准

  • •Age 6m-12y
  • •Impalpable tests (unilateral or bilateral)
  • •Laparoscopy: cord structures entering the inguinal canal.

排除标准

  • •Patient refusing participation in the study.
  • •Any contraindication to laparoscopy
  • •laparoscopy: cord structures passing through an open inguinal canal through which the laparoscopy could be advanced and visualize the tests.
  • •Disorders of sexual differentiation.
  • •Children whose tests became palpable under anesthesia and those with a history of previous inguinal canal exploration (hydrocele or hernia repair) or orchidopexy.

研究组 & 干预措施

Children with impalpable tests

Experimental

For children with impalpable tests before and under anesthesia and by laparoscopy, cord structures could be seen entering the inguinal canal, inguinal exploration will be done.

干预措施: Inguinal exploration (Procedure)

Children with impalpable tests

Experimental

For children with impalpable tests before and under anesthesia and by laparoscopy, cord structures could be seen entering the inguinal canal, inguinal exploration will be done.

干预措施: Laparoscopy (Procedure)

结局指标

主要结局

. Percentage of positive inguinal exploration even by finding a testis or nubbin

时间窗: Intraoperative

To determine the percentage of children with impalpable testis who get benefit from inguinal exploration after laparoscopic identification of cord structures entering the inguinal canal. Inguinal exploration may find a testicular nubbin either in the inguinal region or, most commonly, in the scrotum, which will be excised and sent for histopathology; or a healthy, palpable, undescended testicle amenable to standard orchidopexy.

次要结局

  • Association between these different factors and the presence of inguinal testis in whom impalpable by lap(Preoperative)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mohamed Omar Mohamed

Principal Investigator

Assiut University

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