A Randomized Standard Controlled Clinical trial to evaluate efficacy of Bharangyadi Ghrita in Vataja Kasa.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 64
- 试验地点
- 1
- 主要终点
- 1.To evaluate the efficacy of Bharangyadi Ghrita 10 ml two times a day after meal with lukewarm water and Kantakari Ghrita 10 ml two times a day after meal with lukewarm water in Vataj kasa for 14 days.
研究概览
简要总结
Ayurveda has described the pathogenesis and the treatment of various diseases. Vataj kasa is one of such important Pranavaha Srotas (Respiratory System) vyadhi which has impact on today’s era’s quality of life of an individual. Also in this COVID-19 pandemic it is one of the important factors we should think about. Different modalities of treatment have been explained in Ayurveda to tackle this condition effectively. Respiratory system is the system which is in continuous contact with the external environment since birth throughout the lifetime, so it is most vulnerable to infections. As the prevalence of Vataj Kasa is considerable, Vataj Kasa is one of the common complaint and it is also symptom of various diseases of respiratory system. Vataj Kasa though is not life threatening, it troubles human being as it hinders the day to day activities. According to Ayurveda Shaman line of treatment includes oral administration of medicine is of utmost importance as the administration is very easy and also effective. Cough is a reflex of respiratory tract towards stimulation of cough receptors in mucosa of pharynx, larynx, trachea and bronchi by irritants, foreign body or excess secretion. Treatments of cough mainly consist of treating underlying cause whether infective or non-infective. Apart from specific remedy (antibiotics etc.) cough may be treated as a symptom with pharyngeal demulcents, expectorant, antitussive, antihistamines, bronchodilators etc. In Ayurveda, effective management is described in various Ayurvedic Samhitas. Ayurveda has the best medicine and treatment options for Vataj Kasa (Dry cough). If this treatment is started in beginning of symptoms, the disease can be prevented. Many Ghrita, leha, dhuma, peya, pathya and other simple medicines are found which help in management of Vataj Kasa with minimal efforts. The Vataj Kasa is responsible for many diseases, thus to prevent further progress of the other diseases, it is necessary to cure it at first stage. The present study is carried out to evaluate the effect of Bharangyadi Ghrita on Vataj Kasa. This Bharangyadi Ghrita Is described In Vangasen Samhita, Kasa Prakaran.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Open Label
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Patients presenting with the classical signs and symptoms of Vataj Kasa- Shushka kasa, Hritshool, Parshvashool, Swarbhed, Kshinabala will be taken for study.
- •2.Patients with age group between 20-60 years.
- •3.Patients irrespective of gender, sex, cast, income group and occupation.
排除标准
- •Patients with known case of Tuberculosis, Chronic Obstructive Pulmonary Diseases (COPD) like emphysema, bronchitis, bronchiectasis.
- •Patients with age group more than 60 years,
- •Covid 19 positive patients.
- •Patients having uncontrolled Diabetes mellitus (HbA1c more than 8) and Hypertension (Blood pressure more than 160/110).
- •Immunocompromised patients as AIDS , Cancer etc.
- •Patients with moderate and severe dyspnoea.
- •Patients having SpO2 level below 95%.
- •Patients with hemoptysis.
- •Pregnant ladies and lactating mothers will be excluded.
结局指标
主要结局
1.To evaluate the efficacy of Bharangyadi Ghrita 10 ml two times a day after meal with lukewarm water and Kantakari Ghrita 10 ml two times a day after meal with lukewarm water in Vataj kasa for 14 days.
时间窗: 14 days study with two follow ups on 7th and 14th day
2. To give maximum symptomatic relief to patients after 14 days of treatment
时间窗: 14 days study with two follow ups on 7th and 14th day
3. Relief from symptoms of vataja kasa like shushka kasa, swarbhed, parshvashool, shirshoola after 14 days of treatment.
时间窗: 14 days study with two follow ups on 7th and 14th day
次要结局
- to study the adverse drug effects if any(14 days study with two follow ups on 7th and 14th day)