Comparison of the Clinical Effects of Two Tear Substitutes in Patients With Dry Eye Syndrome

Sun Yat-sen University1 个研究点分布在 1 个国家目标入组 50 人开始时间: 2016年12月最近更新: 2016年12月15日

适应症

干预措施

试验速览

阶段: 不适用
发起方
入组人数: 50
试验地点: 1
主要终点: scale of noninvasive tear breakup time

研究概览研究设计入排标准研究组 & 干预措施结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

With the potential to address evaporative dry eye, Liposic and Tears Naturale Forte have been developed in which phospholipid liposomes are delivered to the tear film via the surface of the closed eyelid. This study compare the effects of Liposic and Tears Naturale Forte application on the lipid and stability of the tear film in dry eye patients.

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Parallel
主要目的: Treatment
盲法: Single (Outcomes Assessor)

入排标准

年龄范围: 20 Years 至 40 Years（Adult）
性别: All
接受健康志愿者: 是

入选标准

•Minimum age of 20 years(range from 20 year to 25 years)
•The value of OSDI is over 12
•NBUT is less 5 seconds
•Schirmer 1 test is less 10mm
•The basical lipid layer grade is 1-2

排除标准

•Any corneal,conjunctival, or eyelid abnormalities; conjunctivitis; current ocular infection; photophobia that may cause reflex tearing or difficulty in evaluating the patient's lipid layer;
•Known allergic sensitivity to any of the ingredients in Liposic or Tears Naturale Forte

研究组 & 干预措施

Liposic

Experimental

Liposic was applied to one eye of patients in this group

干预措施: Liposic (Drug)

Tears Naturale Forte

Experimental

Tears Naturale Forte was applied to one eye of patients in this group

干预措施: Tears Naturale Forte (Drug)