NCT02235844已完成1 期
Allogeneic Transplantation of Human Umbilical Cord Mesenchymal Stem Cells (UC-MSC) for a Single Male Patient With Duchenne Muscular Dystrophy (DMD)
Allergy and Asthma Consultants, Wichita, Kansas2 个研究点 分布在 1 个国家目标入组 1 人开始时间: 2014年9月1日最近更新:
适应症
干预措施
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 1
- 试验地点
- 2
- 主要终点
- Adverse Events
研究概览
简要总结
This research study is designed to evaluate the effects of human umbilical cord mesenchymal stem cells (UC-MSCs), on Duchenne's muscular dystrophy (DMD). The potential muscle regenerative and anti-inflammatory properties of UC MSCs position them as a possible treatment option for DMD. Both of these properties could lead to potential benefits for a DMD patient.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 28 Years 至 31 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Duchenne's Muscular Dystrophy
排除标准
- 未提供
研究组 & 干预措施
Mesenchymal Stem Cells
Experimental
Umbilical Cord Mesenchymal Stem Cells
干预措施: Umbilical Cord Mesenchymal Stem Cells (Biological)
结局指标
主要结局
Adverse Events
时间窗: 3 months after final treatment
No occurrence of adverse events
次要结局
- Change from baseline of weight(3 months after final treatment)
- Change from baseline of Pulmonary Maximum Expiratory Pressure(3 months after final treatment)
- Change from baseline of Pulmonary Forced Vital Capacity(3 months after final treatment)
- Change of muscle diameter (circumferential measurements) from baseline(3 months after final treatment)
- Maximum Change from baseline of Predicted Inspiratory Pressure %(3 months after final treatment)
- Change from baseline of Predicted Maximum Expiratory Pressure %(3 months after final treatment)
- Change from baseline of Predicted Forced Vital Capacity %(3 months after final treatment)
研究者
研究点 (2)
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