EUCTR2010-020466-18-GB
Active, not recruiting
Not Applicable
Can periarticular knee injection of multimodal agents Levobupivicaine, Morphine, Ketorolac and adrenaline improve postoperative pain and function following primary total knee arthroplasty? - Periarticular infiltration following total knee arthroplasty
niversity of Warwick0 sitesAugust 18, 2010
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- niversity of Warwick
- Status
- Active, not recruiting
- Last Updated
- 14 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •All patients undergoing an elective primary unilateral total knee arthroplasty under the care of an orthopaedic consultant at University Hospitals Coventry and Warwickshire NHS trust will be eligible for the trial unless they fit the exclusion criteria.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
- •F.1\.2\.1 Number of subjects for this age range
- •F.1\.3 Elderly (\>\=65 years) yes
- •F.1\.3\.1 Number of subjects for this age range
Exclusion Criteria
- •The following patients will not be eligible for entry to the trial:
- •Those with sufficient cognitive impairment that they would be unable complete questionnaire (cognitive impairment).
- •Those patients who lack capacity under the Mental Capacity Act 2005
- •Those patients with a pre\-operative history of neurological abnormality in the ipsilateral leg e.g. history of stroke, neurogenic pain or previous nerve injury.
- •Those patients having spinal anaesthesia.
- •Those patients with a specific contraindication to the analgesic agents used:
- •?Hypersensitivity reaction
- •?Active or previous peptic ulcer. History of upper gastrointestinal bleeding or perforation, related to previous NSAID therapy.
- •?Haemorrhagic diatheses, including coagulation disorders
- •?Hypersensitivity to ketorolac trometamol or other NSAIDs
Outcomes
Primary Outcomes
Not specified
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