DRKS00010285已完成Unknown
(1,3)-ß-D-glucan based diagnosis of invasive candida infection versus culture based diagnosis in patients with severe sepsis or septic shock and a high risk for invasive candida infection. - CandiSep
Friedrich-Schiller-Universität JenaMedizinische Fakultät0 个研究点目标入组 342 人开始时间: 2016年8月22日最近更新:
适应症
试验速览
- 阶段
- Unknown
- 状态
- 已完成
- 发起方
- 入组人数
- 342
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized controlled study
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 one（—）
- 性别
- All
入选标准
- •Severe sepsis or septic shock
- •Increased risk for invasive candida infection (at least one of the following):
- •> total parenteral nutrition =48 hours
- •> abdominal surgery within the last 7 days
- •> antimicrobial therapy for at least 48 hours within the last 7 days
- •> Acute or chronic renal failure with renal replacement therapy
- •Onset of sepsis no longer than 24 hours
- •Age =18 years
- •Informed consent of the patient or legal representative or delayed consent process is started if patient is incapable of giving informed consent and no legal representative is available.
排除标准
- •Pregnant or lactating women
- •Ongoing invasive candida infection
- •systemic antifungal therapy
- •liver cirrhosis Child C
- •cardiopulmonary bypass within the last 4 weeks
- •treatment with immunoglobulins within the last 14 days
- •immunosuppression (solid organ transplantation, AISA, leukopenia)
- •participation in another intervention study
- •no commitment to full therapy (i.e. DNR order)
- •Infauste Prognose aufgrund von Nebenerkrankungen
- •Kin to or colleague of study personnel
研究者
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