Effects of Blood Flow Restriction During Multiple-joint Eccentric Resistance Training on Muscle Morphology and Function of the Lower Body.
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 2
- 主要终点
- Muscle mass
研究概览
简要总结
The study will determine the effects of adding blood flow restriction to eccentric training to assess whether this increases the improvements of muscle strength and size.
详细描述
Subjects will be randomly assigned to two groups: an eccentric only resistance training group or an eccentric training plus blood flow restriction group. Subjects will train at a moderately low intensity on a multiple-joint eccentric device. Those in the blood flow restriction will wear blood flow restriction cuffs on their upper thighs to reduce blood flow during the brief protocol. The training session will occur twice per week and will last ~5 minutes, including a one minute warm up, a one minute cool down and a three minute workout phase. The training program will last 7 weeks. Testing will be conducted at baseline (following a one session familiarization), 4 weeks and after the end of the 7 week training period. Assessments will focus on muscle strength, function, and morphology (size).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Single (Outcomes Assessor)
盲法说明
The person assessing the outcome measures will be blinded to the group designation of the subjects.
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18-30 years of age
- •currently engaged in some form of resistance training between 1-3 times per week
- •must have been training aerobically, but no more than 3 hours a week for the past six months
排除标准
- •Must not have had any surgery of the lower limbs within the past 1 year period
- •Must not have any neuromuscular disorder (e.g., Muscular dystrophy etc.)
- •< 76 inches tall (in order to fit on the training machine)
- •Maximal strength of < 725 lbs for the eccentric training device
- •If any of the subjects are pregnant or plan to be pregnant in the duration of the protocol.
- •For those randomized to the BFR group, if any of the subject's thighs are too large for the BFR cuffs (greater than 68 cm).
结局指标
主要结局
Muscle mass
时间窗: 7 weeks
dual energy x-ray absorptiometry device (DEXA) the Hologic Horizon W Dual X-ray absorptiometry (Hologic Canada ULC, Mississauga, ON, Canada) will be used to assess appendicular (lower body) mean mass.
Eccentron maximal muscle strength
时间窗: 7 weeks
Eccentric muscle strength will be assessed via Eccentron (BTE Technologies, Inc., USA), an seated isokinetic dynamometer.
Local muscle hypertrophy
时间窗: 7 weeks
Muscle size changes of the quadriceps muscle measured an ultrasound device (GE NextGen LOGIQ, Tampa, Florida, USA).
Muscle function
时间窗: 7 weeks
Vertical jump height will assess 3 maximal countermovement attempts on a jump mat (Just Jump Technologies, Huntsville, AL, USA) that measures jump height based on flight time.
次要结局
- Muscle soreness(7 weeks)
研究者
Brennan Thompson
Principal Investigator
Utah State University