Epigenetic mechanisms in patients undergoing cardiac surgery

• Conditions: R65.9; R65.1; R65.3; Systemic Inflammatory Response Syndrome, unspecified; Systemic Inflammatory Response Syndrome of infectious origin with organ failure; Systemic Inflammatory Response Syndrome of non-infectious origin with organ failure

• Registration Number: DRKS00032718
• Lead Sponsor: niversitätsklinikum Heidelberg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-10-12
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 110

Inclusion Criteria

1.) Age >18 years
2.) Elective cardiac surgery patients with planned use of a heart-lung machine
3.) written declaration of consent

Exclusion Criteria

1.) Age <18 years
2.) Immunosuppressive long-term medication
3.) no declaration of consent available

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Analysis of the influence of epigenetic mechanisms on the level of cell regulation using blood samples, epigenetic studies and PCR

Secondary Outcome Measures

Name	Time	Method
no entry