An Educational Intervention to Improve the Use of Antibiotics in Portuguese Health Professional: Cluster-randomized Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 2,300
- 主要终点
- Change From Baseline Antibiotic Consumption at 18 Months, in Primary Care
研究概览
简要总结
This is a cluster randomised controlled trial covering all general practitioners working in the National Health System (SNS) and all pharmacists working in community pharmacies in the area covered by the Health Region Administration of Center (ARS-C) . A specific educative intervention, designed from gaps detected in knowledge and attitudes with respect to antibiotics and resistance, will be carried out on the intervention group. The control group will not receive any specific intervention.
Hypotheses:
- The attitudes and knowledge towards antibiotics generate habits of prescription by physicians
- The attitudes and knowledge towards to antibiotics generate propensity to dispense antibiotics without prescription by pharmacists
- The identification of the attitudes, knowledge and factors that generate habits of inadequate prescription will allow the design of specific educative interventions to improve the use of antibiotics
- The identification of the attitudes, knowledge and factors that generate propensity to dispense antibiotics without prescription will allow the design of specific educative interventions to antibiotic use
- The interventions designed from gaps detected in knowledge and attitudes with respect to antibiotics and resistance will improve the prescription and dispensation of antibiotics by physicians and pharmacists, respectively.
- The intervention will collaborate in the control of the bacterial resistance.
详细描述
The intervention will consist of group outreach visits (40 minutes), and will be targeted at changing the knowledge-attitudes previously found to be associated with poor prescribing of antibiotics in the case of physicians and propensity to dispense antibiotics without medical prescription in the case of pharmacists.. An observational cohort study of a sample of 1100 primary care physicians and 1200 community pharmacists will be carried out to identify knowledge-attitudes associated with inappropriate prescribing of antibiotics. The independent variables (knowledge-attitudes) will be assessed by a self-administered postal questionnaire and dependent variables are some quantity and quality indicators of the prescribing antibiotics, and consumption data.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All general practitioners working during the period of the study in the National System of Health (SNS)
- •All pharmacists working during the period study in the community pharmacies.
排除标准
- 未提供
结局指标
主要结局
Change From Baseline Antibiotic Consumption at 18 Months, in Primary Care
时间窗: up to 18 months
To quantify antibiotic drug consumption, we used monthly sales data sourced from IMS Health® and we used the quality indicators validated by Coenen S et al., (2007) to calculate monthly prescribing rates.
Antibiotic Monthly Sales Data and Quality Indicators Monthly Prescribing Rates.
时间窗: May 2012- September 2014
antibiotic monthly sales data, obtained from IMS and quality indicators monthly prescribing rates, according to the ESAC indicators.
次要结局
未报告次要终点
研究者
Maria Teresa Herdeiro
Prof
Aveiro University