Health Education Based on We Media to Promote Patient Adherence to HCV Treatment: A Nationwide Online Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 1,000
- 主要终点
- Rate of antiviral therapy
研究概览
简要总结
INTRODUCTION: Hepatitis C virus (HCV) is recognized as the leading cause of chronic liver disease worldwide. However, the screening rate and treatment rate of HCV-infected patients in China is low, which increases the burden of patients and the infection risk of their family members. WeChat, an instant messaging software, is used in a very high proportion in China. Health promotion based on WeChat public platform is a very convenient and effective way of health education. Therefore, this study plans to apply WeChat to conduct health intervention for HCV-infected patients. The objective is to explore the effect of We-media-based health promotion method on the detection rate and treatment rate of HCV-infected and their family members.
METHOD: Recruitment will be conduct in 10 hospitals in Jilin, Beijing, Henan and Anhui provinces. The subjects should be patients new diagnosed with hepatitis C at the hospital and aged 18 to 69. After signing the consent form, eligible participants were selected through the inclusion and exclusion criteria. 1000 participants will be recruited for the trial. After completing an baseline reseach by a online questionnaire, patients will be randomly assigned to receive a targeted short article on HCV weekly or a general health article with no mention of HCV. The intervention will last three months and a follow-up will be conduct at three month after the last intervention.
OUTCOMES: The primary outcome is antiviral therapy. The secondary outcomes are cognition and attitude towards hepatitis C, factors influencing antiviral therapy, time to first treatment and the compliance of treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 69 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Permanent residents in the province
- •Ages 18-69 (inclusive)
- •Both blood anti-HCV test and HCV-RNA test is positive
- •Familiar with the use of mobile phones and WeChat
- •Informed consent and voluntary participation in the study
排除标准
- •Temporary staff who come to the city to work, travel or visit relatives, or those who will be living in other cities for a long time
- •Suffering from other serious diseases
- •Patients with mental disorder or memory disorder
- •Pregnant women or those who have a plan to prepare for pregnancy within one year
- •Refuse to participate in the investigation
结局指标
主要结局
Rate of antiviral therapy
时间窗: 6 months after the first intervention
The rate of antiviral therapy is equal to the number of subjects received antiviral therapy divide by the number of all subjects.
次要结局
- Factors influencing antiviral therapy(6 months after the first intervention)
- The rate of giving up treatment halfway(6 months after the first intervention)
- Time to first treatment(6 months after the first intervention)
- Cognition and attitude towards hepatitis C(6 months after the first intervention)