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Clinical Trials/NCT06615141
NCT06615141
Recruiting
N/A

Immersive Versus Non-immersive Virtual Reality in Enhancing Upper Limb Functions Among Individuals With Subacute Stage Hemiplegia - A Randomized Controlled Trial

Gulf Medical University1 site in 1 country30 target enrollmentMarch 5, 2024

Overview

Phase
N/A
Intervention
Not specified
Conditions
Hemiplegia and/or Hemiparesis Following Stroke
Sponsor
Gulf Medical University
Enrollment
30
Locations
1
Primary Endpoint
Fugl-Meyer Assessment for upper extremity (FMA-UE)
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

The goal of this randomized controlled trial is to compare the effectiveness of immersive virtual reality combined with conventional therapy to the effectiveness of non-immersive virtual reality combined with conventional therapy in enhancing upper limb function in subacute hemiplegic stroke patients.

Detailed Description

The study is a single blinded randomized controlled trial in which the assessor will be blinded. Male and female participants aged between 28-55 years are included in the study. Participants are selected based on inclusion and exclusion criteria and are later randomly assigned to Group 1 and Group 2. Group 1 - Conventional therapy and Immersive Virtual Reality Group 2 - Conventional therapy and Non-Immersive Virtual Reality Primary Outcome measures include the Fugl Meyer Assessment for Upper limb and Graded Wolf Motor Function test for upper limb. Secondary Outcome measure is the Stroke Specific Quality of Life Scale (SS-QOL) Questionnaire. Therapy session starts with 15 minutes of stretching and strengthening exercises of the affected arm followed by 45 minutes of Immersive / Non Immersive virtual reality training. Follow up assessment is done 6 weeks post intervention. The baseline assessment score and follow up assessment scores will be compared.

Registry
clinicaltrials.gov
Start Date
March 5, 2024
End Date
January 5, 2025
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Gulf Medical University
Responsible Party
Principal Investigator
Principal Investigator

Athira George

Principal Investigator

Gulf Medical University

Eligibility Criteria

Inclusion Criteria

  • Individuals aged 28-55 years.
  • Diagnosed with hemiplegia due to stroke.
  • ≤ Grade 2 on Modified Ashworth scale.
  • ≤ Stage 2 on Brunnstrom stages of motor recovery.
  • Score of ≥ 35/36 on Cognitive assessment scale for stroke patients (CASP)

Exclusion Criteria

  • Contraindications for VR therapy, such as severe motion sickness or photosensitive epilepsy, impaired spatial awareness.
  • Pre-existing neurological conditions such as spinal cord injury, Multiple sclerosis and so affecting upper limb function.

Outcomes

Primary Outcomes

Fugl-Meyer Assessment for upper extremity (FMA-UE)

Time Frame: From enrollment to the end treatment at 6 weeks

A valid, reliable, and comprehensive measurement tool with an intra-rater reliability of ICC 0.96 and interrater reliability of ICC 0.98, used to evaluate motor impairment, balance, sensation, and joint function in the upper extremities after stroke.

Graded Wolf Motor function test - The WMFT

Time Frame: From enrollment to the end treatment at 6 weeks

This test is designed to assess motor function, strength, and coordination in individuals with upper extremity impairments. It is a reliable measure with inter-rater reliability of 0.97 and intra-rater reliability of 0.90.

Secondary Outcomes

  • Stroke Specific Quality of Life Scale (SS-QOL)(From enrollment to the end treatment at 6 weeks)

Study Sites (1)

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