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临床试验/CTRI/2026/03/106127
CTRI/2026/03/106127尚未招募4 期

The Analgesic Efficacy of Thoracolumbar Interfascial Plane block (TLIP) versus Erector Spinae Plane block (ESPB) for Thoracolumbarspine surgeries – A Randomised controlled study

Dr Vaishali Waindeskar1 个研究点 分布在 1 个国家目标入组 70 人开始时间: 2026年4月15日最近更新:

试验速览

阶段
4 期
状态
尚未招募
发起方
入组人数
70
试验地点
1

研究概览

简要总结

Surgical management is commonly required for degenerative and traumatic disorders of the thoracolumbar spine, with postoperative pain presenting as a frequent and significant challenge. The erector spinae plane (ESP) block, involves injection of local anesthetic beneath the erector spinae muscle while  the thoracolumbar interfascial plane (TLIP) block targets the plane between the longissimus and multifidus muscles and primarily attenuates pain via blockade of the dorsal rami . Participants  will be divided into 2 groups - Group EP : All patients will receive standard general anaesthesia followed by bilateral Erector spinae block using 20 ml of 0.25% levobupivacaine with 1 ug/kg of dexmedetomidine. (20ml each side )Group TP : All patients will receive standard general anaesthesia followed by bilateral Thoracolumbar interfascial plane block using 20 ml of 0.25% levobupivacaine with 1ug/kg of dexmedetomidine . (20ml each side ) .primary and secondary outcomes will be measured at 2,6,12,24,4 hours .

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant and Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • 18-65 years of age of any sex, ASA(American Society of Anaesthesiologists classification of Physical Status) I-II, scheduled for less than four level lumbar spine surgeries, in which the plan of anaesthesia is GA plus Regional block.
  • Type of surgeries could include but are not restricted to:-
  • Single level laminectomy/laminotomy
  • Lumbar decompression surgeries
  • Posterior lumbar interbody fusion
  • Prolapsed intervertebral disc
  • Single level Microdiscectomy.

排除标准

  • Patient’s refusal to the block procedure Contraindication to regional technique e.g., allergy to local anaesthetic drugs, block site, infection, coagulation disorders.
  • Body mass index>35 kg/m2 Pregnancy Physical or mental disorders that would interfere with the evaluation of pain Patients with skin lesions due to any disease Patient on anti–epileptic drugs/ enzyme inducers as it would affect the metabolism of drugs Local inflammation.

研究者

发起方
Dr Vaishali Waindeskar
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Vasudev shenoy

All India Institute Of Medical Sciences, Bhopal

研究点 (1)

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