Comparison of Time From Symptom Onset to Oseltamivir Access When Oseltamivir is Prescribed by Pharmacists vs. Physicians and the Impact on Symptoms, Oseltamivir Resistance, and Patient Safety
试验速览
- 阶段
- 4 期
- 状态
- 终止
- 入组人数
- 48
- 试验地点
- 15
- 主要终点
- Time from symptom onset to Oseltamivir access
研究概览
简要总结
The main purpose of this study is to see if patients with the flu would receive oseltamivir treatment more quickly if it were prescribed by a pharmacist as compared to a physician, and to see if there is any difference in the effect of treatment on flu symptoms and overall health. Another reason for doing the study is to see how accurately pharmacists can diagnose the flu as compared to physicians. Viruses that are exposed to antiviral medications (like oseltamivir) sometimes develop a resistance to the medication. This means that the medication is no longer as effective in treating the symptoms caused by the virus. The development of viral resistance to oseltamivir will also be followed in this study.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Patients with Oseltamivir Prescription
Patients arriving at the pharmacy with a prescription for Oseltamivir
干预措施: Oseltamivir (Drug)
Patients with signs, symptoms of flu
Patients arriving at the pharmacy with signs, symptoms of flu that the pharmacist diagnoses as having flu and being suitable for pharmacist prescribing of Oseltamivir according to an algorithm.
干预措施: Oseltamivir (Drug)
结局指标
主要结局
Time from symptom onset to Oseltamivir access
时间窗: Confirmed at Visit 1, Day 1
次要结局
- Positive Predictive Value (PPV) of Influenza Clinical Diagnosis(Confirmed at Visit 1, Day 1)
- Oseltamivir Resistance(Confirmed at Visit 1, Day 1 and Visit 2, Day 5)
- Influenza Signs and Symptoms(Collected from Day 1 to Day 5)
- Adverse Events(Collected over 21 days)