Lipid Oxidation of Ready Meals: Reformulation With Antioxidant Phytochemicals
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- University of Aberdeen
- Enrollment
- 16
- Locations
- 1
- Primary Endpoint
- Lipid peroxides
Study Overview
Brief Summary
Consumption of "ready meals" and other convenience foods are rapidly increasing. However, their nutritional value is problematical. For example, many are high in fats which are potentially oxidisable resulting in the formation of toxic end products. Consequently the aim of this study is to assess whether consumption of "ready meals" rich in certain fats leads to a post-prandial increase in lipid oxidation products in plasma and whether this can be ameliorated by reformulating the meals with natural extracts rich in phytochemicals with potential antioxidant activity in the stomach
Detailed Description
Many of these lipid oxidation products such as malondialdehyde are known to be genotoxic and potentially detrimental to health. Consequently the aim of this study is to assess whether consumption of "ready meals" rich in certain fats leads to a post-prandial increase in lipid oxidation products in plasma and whether this can be ameliorated by reformulating the meals with natural extracts rich in phytochemicals with potential antioxidant activity in the stomach.
Diet design requirements:
The basic "ready meal" is a turkey burger consisting of
- 50% fat
- 20% protein
- 30% carbohydrate.
However, there are four experimental forms of the burger.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Basic Science
- Masking
- Single (Investigator)
Eligibility Criteria
- Ages
- 21 Years to 60 Years (Adult)
- Sex
- Male
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •No diagnosed clinical condition
Exclusion Criteria
- •Are taking any medicines prescribed by their GP Have a known allergy to beetroot Are vegan Regularly take nutritional supplements Have given a large blood donation in last three months
Arms & Interventions
Burger and Beetroot Study
Intervention: Burger and Beetroot Study (Other)
Outcomes
Primary Outcomes
Lipid peroxides
Time Frame: up to 24 hours
Indices of oxidised lipids in plasma
Secondary Outcomes
- Blood pressure(up to 24 hours)