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Clinical Trials/NCT01492413
NCT01492413
Completed
Not Applicable

Impact of an Online Behavioral Weight Loss Program Provided With or Without a Fortified Diet Beverage

Baylor College of Medicine3 sites in 2 countries572 target enrollmentOctober 2008

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Overweight
Sponsor
Baylor College of Medicine
Enrollment
572
Locations
3
Primary Endpoint
body weight
Status
Completed
Last Updated
14 years ago

Overview

Brief Summary

This study was designed to test the impact of a 12-week online behavioral modification program for weight loss, with or without a fortified beverage. Subjects are randomized to four conditions: 1) Online Basic Lifestyle Counseling (OBLI); 2) Online Lifestyle Counseling (OLC); 3) OBLI plus a beverage (BEV); 4) OLC + BEV. The three hypotheses were: 1)after 12 weeks, individuals in the OLC condition would lose more weight than those in OBLI; 2) after 12 weeks, the OLC + BEV condition would lose more weight than the OLC condition; and 3) after 12 weeks, the OBLI + BEV condition would lose more weight than the OBLI condition.

Detailed Description

This study tests the impact of an innovative combination of a fortified beverage (a diet cola containing green tea extract, soluble dextrin fiber, and caffeine) and an online support weight loss program in a multi-center randomized clinical trial. The study compares the impact of all combinations of the beverage and the online behavioral modification treatment program over 12 weeks at three treatment center in the US and EU.

Registry
clinicaltrials.gov
Start Date
October 2008
End Date
December 2011
Last Updated
14 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

John P. Foreyt

Professor, Department of Medicine

Baylor College of Medicine

Eligibility Criteria

Inclusion Criteria

  • Body Mass Index (BMI) of 25 to 40;
  • age 18 to 65 years;
  • blood pressure less than 140 mmHg systolic and 90 mmHg diastolic;
  • caffeine intake 100-400 mg/d; and
  • ability to participate in physical activity for a minimum of 150 min/week.

Exclusion Criteria

  • pregnancy, lactation or actively trying to become pregnant;
  • medical illnesses or medications that could affect body weight;
  • cigarette smokers;
  • weight loss of 10 or more pounds in the last 3 months;
  • fasting blood glucose greater than 126mg/dl;
  • participation in a clinical research study that would conflict with the purpose of the current trial; and
  • other factors that in the judgment of the principal investigator may interfere with study participation or the ability to follow the intervention protocol.

Outcomes

Primary Outcomes

body weight

Time Frame: 12 weeks

Body weight is assessed at baseline, 6 and 12 weeks. Body weight is determined using a calibrated scale.

Secondary Outcomes

  • DEXA-determined fat mass(12 weeks)

Study Sites (3)

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