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临床试验/NCT02083198
NCT02083198已完成不适用

A Comparison of High and Low Chloride Containing IV Fluid Solutions in Patients Undergoing Major Surgery and/or ICU Admission

Baxter Healthcare Corporation1 个研究点 分布在 1 个国家目标入组 1,558 人开始时间: 2013年9月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
1,558
试验地点
1
主要终点
Mortality

研究概览

简要总结

This observational study evaluates the impact of high and low chloride containing IV fluids on administrative and clinical outcomes. The study uses a large electronic health dataset and examines patients receiving fluid replacement and resuscitation. The hypothesis is that high chloride solutions are associated with adverse outcomes as measured by administrative data and by clinical parameters.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adults meeting SIRS criteria receiving at least 500 mL of fluid replacement on day of SIRS.

排除标准

  • Receipt of starches or other colloids

结局指标

主要结局

Mortality

时间窗: Hospitalization, Expected Length of inpatient stay is approximately 7 days

Inpatient mortality. Expected Length of inpatient stay is approximately 7 days

次要结局

  • Infections(inpatient hospitalization, Expected Length of inpatient stay is approximately 7 days)
  • Electrolyte disorders(inpatient hospitalizationExpected Length of inpatient stay is approximately 7 days)
  • Length of Stay(inpatient hospitalization, Expected Length of inpatient stay is approximately 7 days)
  • Acute renal failure(inpatient hospitalization, Expected Length of inpatient stay is approximately 7 days)
  • dysrhythmias(inpatient hospitalization, Expected Length of inpatient stay is approximately 7 days)

研究者

申办方类型
Industry
责任方
Sponsor

研究点 (1)

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