Effects of IV Chloride Content on Outcomes
Completed
- Conditions
- Balanced FluidsSIRSPlasmalyte
- Registration Number
- NCT02083198
- Lead Sponsor
- Baxter Healthcare Corporation
- Brief Summary
This observational study evaluates the impact of high and low chloride containing IV fluids on administrative and clinical outcomes. The study uses a large electronic health dataset and examines patients receiving fluid replacement and resuscitation. The hypothesis is that high chloride solutions are associated with adverse outcomes as measured by administrative data and by clinical parameters.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 1558
Inclusion Criteria
- Adults meeting SIRS criteria receiving at least 500 mL of fluid replacement on day of SIRS.
Exclusion Criteria
- Receipt of starches or other colloids
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mortality Hospitalization, Expected Length of inpatient stay is approximately 7 days Inpatient mortality. Expected Length of inpatient stay is approximately 7 days
- Secondary Outcome Measures
Name Time Method Electrolyte disorders inpatient hospitalizationExpected Length of inpatient stay is approximately 7 days Infections inpatient hospitalization, Expected Length of inpatient stay is approximately 7 days Length of Stay inpatient hospitalization, Expected Length of inpatient stay is approximately 7 days Acute renal failure inpatient hospitalization, Expected Length of inpatient stay is approximately 7 days dysrhythmias inpatient hospitalization, Expected Length of inpatient stay is approximately 7 days
Trial Locations
- Locations (1)
Baxter Healthcare
🇺🇸Deerfield, Illinois, United States