Quality of life in glaucoma patients: Comparison of medical therapy, trabeculectomy and glaucoma drainage device
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- HRQoL
研究概览
简要总结
Glaucomais one of the leading causes of preventable blindness, a close second tocataract, characterized by progressive optic neuropathy and correspondingvisual ï¬eld loss. Qualityof Life (QOL) as perceived by patients with focus on leading a healthy andindependent life is an important barometer of the success of any therapeuticmodality be it medical or surgical. This assessment guides clinician’streatment decision, and modifications to home environment facilitating theexecution of day to day house-hold activities. Tothe best of our knowledge, no study from India has compared the QOL in patientswith glaucoma on medical therapy and in post trabeculectomy and GDD placements. With this backgroundin mind we decided to conduct this hospital based cross sectional study to measure and compare the QOL in patients with glaucomareceiving three types of treatment viz medical therapy, trabeculectomy and GDD placement using multipleinstruments which include vision-specific NEIVFQ25 and GQL-15 questionairre enrolling 30 patients of each category.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 40.00 Year(s) 至 90.00 Year(s)（—）
- 性别
- All
入选标准
- •â€¢Group I: Patients of moderate and severe glaucoma on medical therapy for a period of 3 months to 1 year.
- •â€¢Group II: Patients who have undergone glaucoma filtration surgery in the form of trabeculectomy at least 3 months before the study.
- •â€¢Group III: Patients who have undergone a glaucoma drainage device placement at least 3 months before the study.
排除标准
- •Patients with already compromised quality of life owing to physical disability, hearing disability or neuropsychiatric conditions.
- •Patients who had a trabeculectomy/implant surgery within the 3 months preceding the study period.
- •Patients with other eye diseases such as visually significant cataract, disorders affecting the retina like diabetic retinopathy, diabetic maculopathy, hypertensive retinopathy, age related macular degeneration (ARMD).
- •Patients who underwent a cataract surgery in combination with the trabeculectomy in the same sitting (phacotrabeculectomy).
- •Patients of mild glaucoma or those on monotherapy(receiving single drug therapy).
结局指标
主要结局
HRQoL
时间窗: 3 months-1 year
次要结局
未报告次要终点