A clinical trial to study the effect of slow and rapid withdrawal of antiepileptic drugs in patient with epilepsy in epilepsy monitoring unit
Not Applicable
- Conditions
- Health Condition 1: null- drug refractory epilepsy patient admitted in epilepsy monitoring unit
- Registration Number
- CTRI/2016/08/007207
- Lead Sponsor
- Prof Manjari Tripathi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 140
Inclusion Criteria
• Patients admitted in epilepsy monitoring unit (EMU)
•Patient giving consent
Exclusion Criteria
•Patient not giving Consent.
•Patients having history of status epilepticus and Seizure frequency more than 1/day
•Patient with significant non- neurological co-morbidities like chronic cardiac, renal and other systemic diseases.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Difference in the duration of long-term video-EEG completion time between rapid and slow AED taper groups.Timepoint: Time points will be calculated as total days patient admitted in epilepsy monitoring room.
- Secondary Outcome Measures
Name Time Method long term video-EEG diagnostic yield (calculated as a percentage of prerecording question answered upon completion of LTM) in both groupsTimepoint: Time points will be calculated as total days patient admitted in epilepsy monitoring room.;The percentage of patient with ictal onset EEG localization in two groupsTimepoint: Time points will be calculated as total days patient admitted in epilepsy monitoring room.;The percentage of secondary GTCS (sGTCS), 4-hr and 24-hr cluster, status epilepticus, need for midazolam rescue treatment and LTM associated complications in two groupsTimepoint: Time points will be calculated as total days patient admitted in epilepsy monitoring room;The time to first seizure in two groupsTimepoint: Time points will be calculated as total days patient admitted in epilepsy monitoring room.